Table 2

- The genotype frequencies of the Dombrock blood group polymorphism c.793A>G (rs11276) in Western Saudi Arabians compared with African and East Asian populations listed in the 1000 Genomes database.

Western Saudis/1000 genomes populationsDO genotype frequency (n)P-value†Post-hoc
DO*01/01DO*01/02DO*02/02DO*01/01 vs. non - DO*01/01DO*01/02 vs. non - DO*01/02DO*02/02 vs. non - DO*02/02
% (n)P-value‡ (df=1)
Western Saudis0.18 (80)0.5 (220)0.32 (140)----
Africans0.06 (43)0.41 (269)0.53 (349)<0.001<0.0010.002<0.001
ACB0.07 (7)0.4 (38)0.53 (51)<0.0010.0090.064<0.001
ASW0.1 (6)0.42 (26)0.47 (29)0.0350.1050.280.020
ESN0.06 (6)0.38 (38)0.56 (55)<0.0010.0030.037<0.001
GWD0.02 (2)0.42 (48)0.56 (63)<0.001<0.0010.154<0.001
LWK0.09 (9)0.36 (36)0.54 (54)<0.0010.0280.014<0.001
MSL0.09 (8)0.46 (39)0.45 (38)0.0300.5420.4870.022
YRI0.05 (5)0.41 (44)0.55 (59)<0.001<0.0010.084<0.001
East Asians0.01 (6)0.17 (87)0.81 (411)<0.001<0.001<0.001<0.001
CDX0.02 (2)0.16 (15)0.82 (76)<0.0010.004<0.001<0.001
CHB0.02 (2)0.17 (18)0.81 (83)<0.001<0.001<0.001<0.001
CHS0 (0)0.18 (19)0.82 (86)<0.001<0.001<0.001<0.001
JPT0.01 (1)0.19 (20)0.8 (83)<0.001<0.001<0.001<0.001
KHV0.01 (1)0.15 (15)0.84 (83)<0.001<0.001<0.001<0.001

DO: Dombrock, ACB: African Caribbeans in Barbados, ASW: Americans of African ancestry in southwestren United States, ESN: Esan in Nigeria, GWD: Gambian in western divisions in the Gambia, LWK: Luhya in Webuye, Kenya, MSL: Mende in Sierra Leone, YRI: Yoruba in Ibadan, Nigeria, CDX: Chinese Dai in Xishuangbanna, China, CHB: Han Chinese in Beijing, China, CHS: Southern Han Chinese, JPT: Japanese in Tokyo, Japan, KHV: Kinh in Ho Chi Minh City, Vietnam, †calculated Chi-squared p-value using 3×2 contingency tables. A p-value of ≤0.05 was considered significant and can be further analyzed using post-hoc analyses with Bonferroni correction, ‡type I error was corrected by dividing the desired α=0.05 over the number of tests (0.05/3=0.0167), a p-value of ≤0.0167 was considered significant for post-hoc analyses