- Screening efficiency of hemoglobin A2 for thalassemia.
| Groups | Sensitivity | Specificity | PPV | NPV | Youden index |
|---|---|---|---|---|---|
| Precentage | |||||
| Screening efficiency of HbA2=2.5% for α-thalassemia | |||||
| Males | 55.1 | 83.0 | 37.7 | 40.7 | 0.381 |
| Non pregnant women | 67.9 | 68.0 | 81.8 | 49.9 | 0.359 |
| Pregnant women | 71.3 | 44.9 | 74.0 | 55.7 | 0.162 |
| Overall | 67.9 | 71.6 | 50.5 | 83.9 | 0.395 |
| Screening efficiency of HbA2=3.2% for β-thalassemia | |||||
| Males | 95.2 | 98.3 | 96.4 | 97.5 | 0.935 |
| Non pregnant women | 94.9 | 98.6 | 99.0 | 92.1 | 0.935 |
| Pregnant women | 94.8 | 99.1 | 99.0 | 94.9 | 0.939 |
| Total | 94.8 | 98.6 | 98.2 | 95.9 | 0.934 |
PPV: positive predictive value, NPV: negative predictive value, HbA2: hemoglobin A2