Table 4

- Comparison of hydroxyproline level between different groups.

GroupsnMedian (Q1-Q3)Groups differencesP-value*
181.54 (1.40-1.77) µ/mLp<0.01†<0.001*
281.48 (1.29-1.61) µ/mL-
381.31 (1.24-1.42) µ/mL-
481.19 (0.71-1.33) µ/mLp<0.01

Kriskal-Wallis with Scheffe post hoc test was used to assess differences between the groups. Results presented as median (interquartile range: Q1-Q3) due to nonparametric distribution. Group 1 versus group 4, *Comparison of hydroxyproline between groups, group 1: control, group 2: spongostane group, group 3: low-dose berberine (BBR), group 4: high-dose BBR