- Clinicopathological parameters of tumors (N=570).
| Parameters and total number of cases | n (%) | Coxa immunoexpression | P-values | |
|---|---|---|---|---|
| Negative | Positive | |||
| Type of tissue | ||||
| Breast cancer | 570 (100) | 331 (57.3) | 239 (42.7) | 0.034 |
| Normal breast | 52 (100) | 38 (73.1) | 14 (26.9) | |
| Gender | ||||
| Male | 5 (0.9) | 2 (40.0) | 3 (60.0) | 0.351* |
| Female | 565 (99.1) | 329 (58.2) | 236 (41.8) | |
| Age | ||||
| <50 years | 312 (54.7) | 186 (59.6) | 126 (40.4) | 0.240* |
| ≥50 years | 258 (45.3) | 145 (56.2) | 113 (43.8) | |
| Grade | ||||
| Grade 1 | 95 (16.7) | 64 (67.4) | 31 (32.6) | 0.193* |
| Grade 2 | 285 (49.8) | 160 (56.1) | 125 (43.9) | |
| Grade 3 | 190 (33.5) | 107 (56.3) | 83 (43.7) | |
| Invasive ductal | 489 (88.9) | 290 (59.3) | 199 (40.7) | 0.130* |
| Others | 71 (11.1) | 36 (50.7) | 35 (49.3) | |
| Tumor size (n=492) | ||||
| <3 | 181 (36.8) | 111 (61.3) | 70 (38.7) | 0.112 |
| 3-6 | 229 (46.5) | 129 (56.3) | 100 (43.7) | |
| >7 | 82 (16.7) | 39 (47.6) | 43 (52.4) | |
| Pathological stage (n=495) | ||||
| Low stage | 333 (67.3) | 207 (62.2) | 126 (37.8) | 0.001* |
| High stage | 162 (32.7) | 75 (46.3) | 87 (53.7) | |
| Nodal metastasis (n=478) | ||||
| Negative | 169 (35.4) | 96 (56.8) | 73 (43.2) | 0.470* |
| Positive | 309 (64.6) | 173 (56.0) | 136 (44.0) | |
| Distant metastasis (n=450) | ||||
| Negative | 389 (86.4) | 237 (69.9) | 152 (39.1) | 0.003* |
| Positive | 61 (13.6) | 25 (41.0) | 36 (59.0) | |
| Lymphovascular invasion (n=412) | ||||
| Negative | 225 (54.6) | 138 (61.3) | 87 (38.7) | 0.034* |
| Positive | 187 (45.4) | 97 (51.9) | 90 (48.1) | |
| Surgical margins (n=445) | ||||
| Negative | 377 (84.7) | 217 (57.6) | 160 (42.4) | 0.999* |
| Positive | 68 (15.3) | 39 (57.4) | 29 (42.6) | |
| Local disease recurrence (n=300) | ||||
| Negative | 220 (73.3) | 132 (60.0) | 88 (40.0) | 0.072* |
| Positive | 80 (26.7) | 39 (48.7) | 41 (51.3) | |
Values are presented as numbers and percentage (%).*Chi-square test