Table 2

- Effect of Gardinia latifolia extract (GLE) on metabolic indices in high fat diet-streptozotocin diabetic rats

Groups	Fasting serum insulin mmol/L	Fasting blood glucose mmol/L	HOMA-IR
Normal control	10.33 ± 0.88	4.20 ± 0.16	1.94 ± 0.22
Diabetic control	26.67 ± 0.88 ^*	9.81 ± 0.30^*	11.65 ± 0.66^*
Diabetic + Metformin (STD)	17.00 ± 1.15***	5.61 ± 0.25^{^‡}	4.24 ± 0.26^{^‡}
Diabetic + GLE 250mg/kg p.o	22.33 ± 0.67	8.09 ± 0.26^{^†}	8.03 ± 0.37
Diabetic + GLE 500 mg/kg p.o	18.67 ± 0.88 ^{^†}	5.70 ± 0.21^{^‡}	4.74 ± 0.32^{^‡}

Each value indicates mean ± standard of mean. One-way analysis of variance followed by post-hoc Tukeys test for multiple comparisions.

↵* p<0.001 compared to normal control group;
↵† p<0.01,
↵‡ p<0.001 compared to diabetic control group. HOMA-IR: homeostatic model assessment of insulin resistance, p.o: per oral