- Clinical characteristics and laboratory parameters of survivor and nonsurvivor patients (N=94).
| Variables | ICU survivors (n=44) | ICU nonsurvivors (n=50) | P-values* |
|---|---|---|---|
| Age | 32.5 (27-87) | 72 (41-90) | <0.001 |
| Gender, n (%) | |||
| Female Male | 11 (30.6) 33 (56.9) | 25 (69.4) 25 (43.1) | 0.013 |
| APACHE-II score | 10 (2-18) | 26.5 (11-50) | <0.001 |
| GCS | 15 (3-15) | 13 (3-15) | <0.001 |
| MV duration days | 0 (0-36) | 5 (1-58) | <0.001 |
| LOS ICU (days) | 6.5 (2-43) | 10.5 (2-58) | 0.062 |
| Hemoglobin (gr/dL) | 12.7 (7.5-16.1) | 12.65 (8-15.7) | 0.655 |
| WBC (x109/L) | 8.92 (2.83-24.67) | 9.05 (0.59-39.90) | 0.218 |
| Lymphocyte (x109/L) | 0.735 (0.20-3.91) | 0.64 (0.80-2.59) | 0.102 |
| Neutrophile (x109/L) | 7.18 (2.17-22.98) | 8.11 (0.44-36.0) | 0.056 |
| NLR | 8.6 (0.06-31.0) | 12.41 (0.95-90.44) | 0.026 |
| Platelet (x109/L) | 288 (81-662) | 233.5 (38-464) | 0.234 |
| D-Dimer (mg/L) | 2.02 (0.30-35.2) | 2.8 (0.4-35.2) | 0.342 |
| CRP (g/L) | 0.092 (0.005-0.293) | 0.139 (0.008-0.740) | 0.099 |
| Procalcitonin (µg/L) | 0.165 (0.03-27.70) | 0.180 (0.03-32.40) | 0.285 |
| Ferritin (µg/L) | 733.0 (28-19000) | 741.0 (77-7934) | 0.880 |
| IL-6 (pg/ml) | 46.1 (4.7-235.0) | 72.00 (4.99-8490.0) | 0.022 |
| AST (U/L) | 41.5 (4-360) | 48.0 (6-630) | 0.195 |
| ALT (U/L) | 35.0 (6-89) | 36.5 (8-490) | 0.773 |
| Creatinine (mg/dL) | 0.88 (0.40-10.72) | 0.99 (0.46-43.0) | 0.544 |
| Diaphragm thickness (mm) | |||
| DT anterior right DT anterior left DT middle right DT middle left Total median DT | 72 (41-90) 3.75 (1.6-7.7) 2.95 (1.3-5.1) 2.6 (0.8-4.9) 3.41 (1.75-5.78) | 62.5 (27-87) 2.9 (0.9-6.2) 2.3 (1.2-6.5) 2.25 (0.7-6.1) 2.95 (1.00-6.40) | 0.009 0.014 0.038 0.054 0.009 |
↵* Variables with non-normal distribution are presented as median (minimum-maximum) and Mann-Whitney-U test was used. APACHE-II: acute physiology and chronic health evaluation-II, GCS: Glasgow coma scale, MV: mechanical ventilation, LOS: length of stay, ICU: intensive care unit, WBC: white blood cell, NLR: neutrophil to lymphocyte ratio, CRP: C-reactive protein, IL-6: interleukin-6, AST: aspartate aminotransferase, ALT: alanine aminotransferase, DT: diaphragm thickness