- Clinical characteristics and laboratory parameters of mechanical ventilation and non-mechanical ventilation patients (N=94).
Variables | Non-MV (n=38) | MV (n=56) | P-values* |
---|---|---|---|
Age | 62.5 (27-87) | 72 (34-90) | 0.002 |
Gender, n(%) | |||
Female Male | 10 (27.8) 28 (48.3) | 26 (72.2) 30 (51.7) | 0.049 |
APACHE-II score | 8.5 (2-18) | 25 (7-50) | <0.001 |
GCS | 15 (8-15) | 13 (3-15) | <0.001 |
LOS ICU (days) | 6 (2-25) | 11.5 (2-58) | <0.001 |
Hemoglobin (gr/dL) | 12.95 (7.5-16.1) | 12.55 (8.0-15.7) | 0.322 |
WBC (x109/L) | 8.54 (2.83-18.94) | 9.48 (0.58-39.90) | 0.059 |
Lymphocyte (x109/L) | 0.72 (0.21-3.91) | 0.66 (0.08-2.59) | 0.162 |
Neutrophile (x109/L) | 6.82 (2.17-17.55) | 8.11 (0.44-36.0) | 0.017 |
NLR | 8.55 (1.91-31.0) | 12.55 (0.06-90.44) | 0.010 |
Platelet (x109/L) | 273.5 (85-662) | 240.5 (38-598) | 0.535 |
D-Dimer (mg/L) | 1.81 (0.30-35.2) | 2.8 (0.40-35.2) | 0.126 |
CRP (g/L) | 0.081 (0.005-0.293) | 0.134 (0.008-0.740) | 0.058 |
Procalcitonin (µg/L) | 0.155 (0.03-27.70) | 0.180 (0.03-32.40) | 0.174 |
Ferritin (µg/L) | 566.5 (28-19000.0) | 788.5 (77-7934) | 0.523 |
IL-6 (pg/ml) | 43.15 (4.7-235.0) | 66.9 (4.99-8490.0) | 0.027 |
AST (U/L) | 41.5 (4-360) | 48.0 (6-630) | 0.189 |
ALT (U/L) | 35 (6-89) | 36.5 (8-490) | 0.689 |
Creatinine (mg/dL) | 0.90 (0.61-10.72) | 0.95 (0.40-43.0) | 0.644 |
Diaphragm thickness (mm) | |||
DT anterior right DT anterior left DT middle right DT middle left Total median DT | 4.35 (2.1-6.8) 3.8 (1.6-7.7) 3.25 (1.3-5.1) 2.6 (0.8-4.9) 3.46 (1.75-5.78) | 3.6 (1.2-7.1) 3.6 (0.9-6.2) 2.4 (1.2-6.5) 2.25 (0.7-6.1) 3.03 (1.00-6.40) | 0.009 0.014 0.024 0.034 0.006 |
↵* Variables with non-normal distribution are presented as median (minimum-maximum) and Mann-Whitney-U test was used. MV: mechanical ventilation, APACHE-II: acute physiology and chronic health evaluation-II, GCS: Glasgow coma scale, MV: mechanical ventilation, LOS: length of stay, ICU: intensive care unit, WBC: white blood cell, NLR: neutrophil to lymphocyte ratio, CRP: C-reactive protein, IL-6: interleukin-6, AST: aspartate aminotransferase, ALT: alanine aminotransferase, DT: diaphragm thickness