- Demographics and clinical characteristics of subjects in baseline assessment.
| Characteristics | mean±SD |
|---|---|
| Gender (male) | 38 (100%) |
| Age (years) | 62.2 ± 6.9 |
| BMI (kg/m2) | 20.7 [19.2, 23.9] |
| Smoking history (pack years) | 40.0 [30.0, 60.0] |
| Duration of smoking abstinence (years) | 4.0 [0.5, 6.0] |
| COPD history (years) | 8.0 [6.0, 10.5] |
| GOLD stage | Stage III: 18 (47.4%) Stage IV: 20 (52.6%) |
| PaO2 (mmHg) | 72.28 ± 8.06 |
| PaCO2 (mmHg) | 49.00 ± 8.50 |
| SaO2 (%) | 93.23 ± 2.26 |
| Potential of hydrogen | 7.37 ± 0.04 |
| HCO3- (mmcl/L) | 27.29 ± 4.05 |
| Post-BD FEV1 (L) | 0.85 ± 0.28 |
| Post-BD FEV1 (% of predicted) | 30.78 ± 10.22 |
| Post-BD FVC (L) | 2.27 ± 0.76 |
| Post-BD FVC (% of predicted) | 63.53 ± 20.28 |
| Post-BD FEV1/FVC (%) | 38.17 ± 9.30 |
| Post-BD RV (L) | 6.12 ± 1.43 |
| Post-BD RV (% of predicted) | 263.78 ± 62.75 |
| Post-BD TLC (L) | 8.75 ± 1.54 |
| Post-BD TLC (% of predicted) | 138.99 ± 23.81 |
| Post-BD RV/TLC (%) | 69.76 ± 9.21 |
| 6MWD (m) | 287.06 ± 98.54 |
| mMRC (points) | 3.0 [2.0, 3.0] |
Values are presented as mean ± standard deviation (SD) or median (interquartile range). COPD: chronic obstructive pulmonary disease, GOLD: Global Initiative for Chronic Obstructive Lung Disease, BMI: body mass index, post-BD: post-bronchodilator, FEV1: forced expiratory volume in 1 second, FVC: forced vital capacity, RV: residual volume, TLC: total lung capacity, 6MWD: 6-minute walk distance, mMRC: modified Medical Research Council, HCO3: bicarbonate