- Summary of the primary renal lymphoma cases from 2 tertiary hospitals in the Western regions of Saudi Arabia.
| Patient no. | Age/gender | Specimen | Site | Clinical presentation | Diagnosis | Bone marrow | Radiological findings |
|---|---|---|---|---|---|---|---|
| 1 | 50/M | Biopsy | Left kid | Palpable mass and hematuria | DLBCL | -ve | CT: hypodense lesion in the left kid. The spleen and liver are normal. No significantly enlarged LNs. |
| 2 | 56/M | Biopsy | Right kid | Hematuria, flank pain | DLBCL | -ve | US: hypoechoic tumor with enlarged retrocaval lymph nodes. The spleen and liver are normal. |
| 3 | 59/F | Biopsy, referral | Right kid | Hematuria, weight loss | DLBCL | Not carried out | CT: hypodense lesion in the right kid (3.4x3.2x3 cm). No enlarged lymph nodes. Normal spleen and liver |
| 4 | 61/M | Biopsy, referral | Left kid | Palpable mass and hematuria | DLBCL | -ve | CT: enhancing mass involving left kid There are enlarged lymph nodes in paracaval region. The spleen and liver are normal. |
| 5 | 63/F | Biopsy | Left kid | Flank pain | DLBCL | Not available | Not available |
| 6 | 23/M | Biopsy | Left kid | Abdominopelvic pain | Burkitt’s lymphoma | -ve | CT: multiple hypodense lesions involving left kid. No enlarged lymph nodes. Normal spleen and liver |
| 7 | 24/M | Biopsy | Right kid | Flank pain and mild renal impairment | DLBCL | -ve | US: swollen right kid with paraaortic lymph node enlargement. |
| 8 | 39/M | Biopsy | Kid, bilateral | Chronic renal failure, bilaterally enlarged kid suggestive of glomerulonephritis | Burkitt’s lymphoma | -ve | CT: both kids enlarged with multiple hypodense lesions. No enlarged lymph nodes. Normal spleen and liver |
| 9 | 53/M | Biopsy | Right kid | Hematuria, loss weight for 2 months, known hypothyroid and chronic renal failure | DLBCL | -ve | CT: hypodense lesion in the right kid. The spleen and liver are normal. No significantly enlarged LNs. |
| 10 | 4/M | Biopsy | Kid, bilateral | Bilateral renal enlargement with hepatomegaly | Burkitt’s lymphoma | -ve | CT: both kids are enlarged with no defined focal lesions. There are a few periaortic lymph nodes. Enlarged spleen with no focal lesion. Normal liver. CT of orbits: this is involvement of both orbits and both maxillary sinuses. |
| 11 | 36/F | Biopsy | Kid, bilateral | Epistaxis, abdominal pain, vomiting, and bilateral enlarged kid | DLBCL | -ve | CT: significant intraabdominal lymphomatous infiltrative disease involving the abdominal organs namely both kids, liver, gallbladder, pancreas, adrenals, and intraabdominal and pelvic lymph nodes. |
| 12 | 52/F | Biopsy | Left kid | Left renal mass | DLBCL | -ve | CT: perinephric soft tissue lesion is seen involving the right kid (2.8x0.8 cm). No enlarged lymph nodes. The left kid is atrophic. Liver, spleen, and pancreas adrenal glands are normal. |
| 13 | 76/F | Biopsy | Left kid | Left renal mass, hematuria | DLBCL | -ve | CT: hypodense lesion in the left kid (3.6x4.3x3.4 cm). Similar lesion infiltrating focally the mid-portion of descending colon measuring (2.0x3.5 cm). There are multifocal hypodense splenic lesions. The pelvic organs are unremarkable. |
| 14 | 41/M | Radical nephrectomy | Right kid | Right kid mass with enlarged paraaortic lymph node | DLBCL | -ve | CT: hypodense lesion with enlarged lymph nodes in paracaval region just below the level of renal vein measuring 2.3 cm. |
| 15 | 53/F | Biopsy | Right kid | Right renal mass and flank pain | DLBCL | -ve | CT: enhanced lesion in the right kid (4.6x3.9 cm). It shows slightly more extension towards the renal hilum. The left kid, liver, and spleen are unremarkable. |
| 16 | 61/M | Biopsy | Transplanted kid | Renal mass, flank pain | PTLD, monomorphic, monoclonal, and EBV associated-B cell/DLBCL | Not carried out | CT: large enhancing retroperitoneal mass encasing and involving transplanted kid. There are multiple retroperitoneal, retrocaval, and bilateral inguinal lymph node enlargement. |
| 17 | 44/M | Biopsy | Transplanted kid | Renal mass | PTLD, monomorphic, monoclonal, and EBV associated-B cell/DLBCL | -ve | CT: enhancing mass involving transplanted kid associated with enlarged retrocaval lymph nodes. |
Kid: kidney, M: male, F: female, DLBCL: diffuse large B-cell lymphoma, PTLD: post-transplant lymphoproliferative disorder, EBV: Epstein-Barr virus, -ve: negative, LNs: lymphoid neoplasms, CT: computed tomography, US: ultrasound