- Genotype and allele frequencies of the selected cytochrome P450 2D6 single nucleotide polymorphisms in the study sample (N=107).
| SNPs | Genotypes (N=107) | Alleles (N=214) | P-values (for HWE) | |||
|---|---|---|---|---|---|---|
| rs1080985 | G/G | G/C | C/C | G | C | 0.90 |
| 56 (52.3) | 43 (40.2) | 8 (7.5) | 155 (72.4) | 59 (27.6) | ||
| rs28624811 | G/G | G/A | A/A | G | A | 0.77 |
| 30 (28.0) | 52 (48.6) | 25 (23.4) | 112 (52.3) | 102 (47.7) | ||
| rs1065852 | G/G | G/A | A/A | G | A | <0.001 |
| 80 (74.8) | 14 (13.1) | 13 (12.2) | 174 (81.3) | 40 (18.7) | ||
| rs28371725 | C/C | C/T | T/T | C | T | 0.86 |
| 76 (71.0) | 29 (27.1) | 2 (1.9) | 181 (84.6) | 33 (15.4) | ||
| rs1135840 | G/G | G/C | C/C | G | C | 0.36 |
| 40 (37.4) | 55 (51.4) | 12 (11.2) | 135 (63.1) | 79 (36.9) | ||
| Values are presented as numbers and precentages (%). P-values above 0.05 represents consistency of CYP2D6 genotypes with HWE principle. HWE: Hardy-Weinberg equilibrium, SNPs: single nucleotide polymorphisms | ||||||