- Low-density-lipoprotein-cholesterol (LDL-C) levels throughout the study (N=126).
| LDL-C targets | n(%) | 95% CI | |
|---|---|---|---|
| <130 mg/dL | 118 (93.7) | 87.9 – 97.2 | |
| <100 mg/dL | 106 (84.1) | 76.6 – 90.0 | |
| <70 mg/dL | 77 (61.1) | 52.0 – 69.7 | |
| <50 mg/dL | 42 (33.3) | 25.2 – 42.3 | |
| 55-70 mg/dL | 23 (18.2) | 11.5% – 25.0% | |
| <55 mg/dL | 54 (42.9) | 34.2% – 51.5% | |
| LDL-C levels, in mg/dL* | Mean ± SD | Median (Q1;Q3) | |
| within 2 years of the study | 112.6 ± 43.03 | 111.0 (78.5;141.9) | |
| at baseline | 115.8 ± 46.5 | 112.9 (81.8;145.8) | |
| at the 3-month visit | 63.4 ± 29.5 | 59.0 (43.0;76.6) | |
| at the 6-month visit | 69.8 ± 35.8 | 60.2 (44.0;89.4) | |
| at LDL-C target assessment | 69.0 ± 33.4 | 60.2 (45.6;90.0) | |
| absolute change from baseline | -46.4 ± 49.5* | -45.0 (-77.8;-10.4) | |
| relative change from baseline, in percentage | -32.8 ± 35.1* | -39.4 (-60.0;-11.9) | |
| Time from baseline to target achievement assessment (weeks) | 21.7 ± 7.9 | 24.9 (15.9;27.3) | |
| ≥50% decrease in LDL-C level from baseline | n (%) | ||
| at the 3-month visit at the 6-month visit at LDL-C target assessment | 53 (62.4) out of 85 43 (59.7) out of 72 83 (62.6) out of 115 | ||
| ≥ 50% decrease in LDL-C level AND LDL-C levels < 55 mg/dL | 26 (20.6) out of 126 | ||
| CI: confidence interval, LDL-C: low-density lipoprotein cholesterol, Q1; Q3: first and third quartile range, SD: standard deviation. *p<0.001, *Reference value for LDL-C: ≤ 115 mg/dL in patients at low CV risk12,23 | |||