Table 1

- Baseline characteristics of mothers and neonates between 2 groups.

CharacteristicCase (n=66)Control (n=134)P-value
Gestational age (week)a35.1±3.2735±3.720.818
<28 week0 (0)5 (3.7) 
<32 week8 (12)20 (14.9) 
<37 week35 (53)31 (23) 
≥37 week23 (34.8)78 (58) 
Birthweight (kg)a2.28±0.682.32±0.810.744
<1kg1 (1.5)5 (3.7) 
<1.5kg5 (7.5)19 (14.1) 
<2.5kg37 (56)52 (38.8) 
≥2.5kg23 (35)58 (43.4) 
Gender male, n (%)42 (63.6)79 (58.9)0.524
Caesarean section50 (75.7)68 (50.7)0.001**
Twins or multiplets10 (15.1)12 (8.9)0.232
Intrauterine distress8 (29.0)12 (23.1)0.483
SGA, n (%)12 (18.1)6 (4.47)0.001**
Vitamin K2 level(ng/mL)a0.05±0.0250.446±0.180.000**
Apgar score at 1 minb10(9, 10)10(8, 10)0.849
Apgar score at 5 minb10(10, 10)10(10, 10)0.489
Apgar score at 5 minb10(10, 10)10(10, 10)0.914
PT(S)a15.18±0.2914.98±0.240.621
APTT(S)a53.59±1.4154.36±1.250.943
FIB (g/L)b1.57 (1.25, 1.98)1.6(1.25, 2.6)0.385
Blood glucose (mmol/L)a4.3±0.184.4±0.140.567
Serum Ca(mmol/L)a1.05±0.211.09±0.280.268
Serum P(mmol/L)a1.95±0.211.95±0.2230.837
Maternal, n (%)   
Maternal age (year)b31 (27, 33)30 (26, 34)0.227
PROM18 (27.3)17 (12.7)0.011*
Placental abnormality6 (9.1)5 (3.7)0.118
Antenatal steroid25 (37.9)13 (9.7)0.000**
Gestational diabetes17 (25.8)15 (11.2)0.008**
Preeclampsia/eclampsia5 (7.5)10 (7.4)0.9
  • SGA: small-for-gestational age, PT: prothrombin time, APTT: activated partial thromboplastin time, FIB: fibrinogen. PROM: premature rupture of membranes, Ca: calcium, P: phosphatase.

  • a Mean ± SD(standard deviation);

  • b IQR: interquartile range,

  • * p<0.05,

  • ** p<0.01.

  • Normal values: vitamin K2 level-(0.1-0.86 ng/ml); PT-(10.6-14.3s); APTT-(26-40s); FIB-(2-4g/L); blood glucose-(3.9-6.0mmol/L); serum Ca-(1.15-1.33mmol/L); serum P-(1.45-2.1mmol/L)