- Frequencies and associations of demographics, clinical findings, and diagnosis with p53-immunostain.
| Demographics | Negative n=12 | Diffuse positive n=2 | Focal positive n=29 | P-value | |
|---|---|---|---|---|---|
| Gender | Female | 7 (58.0) | 1 (50.0) | 13 (45.0) | 0.747 |
| Male | 5 (42.0) | 1 (50.0) | 16 (55.0) | ||
| Age group | <50 | 1 (8.5) | 1 (50.0) | 8 (27.5) | 0.268 |
| 50-60 | 4 (33.0) | 1 (50.0) | 8 (27.5) | ||
| 61-70 | 6 (50.0) | 0 (0) | 6 (21.0) | ||
| >70 | 1 (8.5) | 0 (0) | 7 (24.0) | ||
| H. pylori | No | 10 (83) | 1 (50.0) | 23 (79.0) | 0.632 |
| Yes | 2 (17.0) | 1 (50.0) | 6 (21.0) | ||
| Intestinal metaplasia | No | 12 (100) | 1 (50.0) | 24 (83.0) | 0.127 |
| Yes | 0 (0.0) | 1 (50.0) | 5 (17.0) | ||
| Anemia | No | 3 (25.0) | 2 (100) | 10 (34.5) | 0.150 |
| Yes | 9 (75.0) | 0 (0) | 19 (65.5) | ||
| Abdominal pain | No | 2 (17.0) | 1 (50.0) | 6 (21.0) | 0.632 |
| Yes | 10 (83.0) | 1 (50.0) | 23 (79.0) | ||
| Surgery | No | 6 (50.0) | 0 (0.0) | 11 (38.0) | 0.150 |
| Yes | 5 (42.0) | 0 (0.0) | 9 (31.0) | ||
| Unknown | 1 (8.0) | 2 (100) | 9 (31.0) | ||
| Chemotherapy | No | 7 (58.0) | 0 (0.0) | 11 (38.0) | 0.127 |
| Yes | 4 (33.5) | 0 (0) | 9 (31.0) | ||
| Unknown | 1 (8.5) | 2 (100) | 9 (31.0) | ||
| Esophago-gastroduodenoscopy | Mass | 9 (75.0) | 1 (50.0) | 15 (52.0) | 0.521 |
| Ulcer | 3 (25.0) | 1 (50.0) | 12 (41.0) | ||
| Unknown | 0 (0) | 0 (0) | 2 (7.0) | ||
| Mortality | Alive | 2 (17.0) | 1 (50.0) | 8 (28.0) | 0.467 |
| Dead | 10 (83.0) | 1 (50.0) | 21 (72.0) | ||
| Diagnoses of gastric cancer (percentage of diagnosis cases): | |||||
| Intestinal type adenocarcinoma (n=6) | Yes | 1 (17.0) | 1 (17.0) | 4 (67.0) | 0.377 |
| No | 11 (30.0) | 1 (3.0) | 25 (68.0) | ||
| Signet ring cell adenocarcinoma (n=29) | Yes | 9 (31.0) | 1 (3.5) | 19 (65.5) | 0.747 |
| No | 3 (21.0) | 1 (7.0) | 10 (71.0) | ||
| Gastrointestinal stromal tumor (n=2) | Yes | 1 (50.0) | 0 (0) | 1 (50.0) | 0.550 |
| No | 11 (27.0) | 2 (5.0) | 28 (68.0) | ||
| Diffuse large B-cell lymphoma (n=5) | Yes | 0 (0) | 0 (0) | 5 (100) | 0.453 |
| No | 12 (32) | 2 (5) | 24 (63.0) | ||
| MALToma (n=1) | Yes | 1 (100) | 0 (0.0) | 0 (0.0) | 0.326 |
| No | 11 (26) | 2 (5.0) | 29 (69) | ||
Values are presented as numbers and percentages (%). **Significant at p<0.01. *Significant at p<0.05. P-value was calculated using Fisher’s exact test. Ten patients’ paraffin blocks were not available.