- Baseline data of included patients (N=16).
| Variables | n (%) |
|---|---|
| Gender | |
| Male | 7 (43.8) |
| Female | 9 (56.3) |
| Age at diagnosis (year) | 3 (1.81-5.25) |
| Total number of procedures | 6.5 (4.75-13.5) |
| Length of follow-up (month) | 56 (12.8-97.8) |
| Histology of tissue specimen | |
| Squamous papilloma | 11 (68.8) |
| Squamous papilloma with HPV | 2 (12.5) |
| Squamous papilloma with HPV P16 | 2 (12.5) |
| Squamous papilloma, with HPV-6, and HPV-11 | 1 (6.3) |
| Complications | |
| Anterior commissure adhesion | 1 (6.3) |
| Disseminated RRP (pulmonary) | 1 (6.3) |
| Extralaryngeal spread | 5 (31.2) |
| Nasal vestibule | 1 (6.3) |
| Posterior pharyngeal wall | 1 (6.3) |
| Trachea | 1 (6.3) |
| Uvula | 2 (12.5) |
| Posterior glottic stenosis | 1 (6.3) |
| None | 8 (50.0) |
| First Derkay score | 17 (12-19.8) |
| MTI | 0.215 (0.107-0.362) |
| Patients treated with cidofovir | 12 (75.0) |
| Patients treated with avastin | 10 (62.5) |
| Change in Derkay’s score | -11 (-13.3, -8.5) |
| Clinical outcome | |
| Complete remission | 5 (31.3) |
| Partial remission | 7 (43.8) |
| Persistent disease | 4 (25.0) |
Values are presented as numbers and precentages (%) or median and interquartile range (IQR). HPV: human papilloma virus, RRP: recurrent respiratory papillomatosis, MTI: mean treatment intervals