- Univariate and multivariate regression results of the association between the change in Derkay score and other variables.
| Variables | Univariate regression | Multivariate regression | ||||
|---|---|---|---|---|---|---|
| Regression coefficient | 95% CI | P-values | Regression coefficient | 95% CI | P-values | |
| Gender (male) | -2.25 | (-7.87, 3.36) | 0.404 | - | - | - |
| Age at diagnosis in years | -0.446 | (-1.25, 0.358) | 0.254 | - | - | - |
| Length of follow-up in months | -0.007 | (-0.06, 0.049) | 0.774 | - | - | - |
| Histology of specimen (squamous papilloma) | ||||||
| Squamous papilloma and HPV | 3.275 | (-4.914, 11.46) | 0.401 | - | - | - |
| Squamous papilloma and HPV P16 | 7.773 | (-0.414, 15.96) | 0.061 | - | - | - |
| Squamous papilloma, HPV-6, and HPV-11 | 0.273 | (-10.85, 11.4) | 0.958 | - | - | - |
| Complication | ||||||
| Extra-laryngeal spread | -1.88 | (-8.44, 4.69) | 0.542 | - | - | - |
| Posterior glottic stenosis | -5.87 | (-18.08, 6.33) | 0.312 | - | - | - |
| Anterior commissure adhesion | -3.88 | (-16.08, 8.33) | 0.499 | - | - | - |
| Disseminated RRP (pulmonary) | -8.88 | (-21.08, 3.33) | 0.138 | - | - | - |
| First Derkay score | -0.424 | (-0.764, -0.083) | 0.018 | -0.337 | (-0.683, 0.009) | 0.056 |
| MTI | -4.52 | (-18.4, 9.32) | 0.496 | - | - | - |
| Patients treated with cidofovir (non treated) | -5.83 | (-11.5, -0.143) | 0.045 | -4.008 | (-9.48, 1.46) | 0.138 |
| Patients treated with avastin (not treated) | -1.13 | (-7, 4.73) | 0.685 | - | - | - |
| Total number of procedures | -0.151 | (-0.592, 0.29) | 0.476 | - | - | - |
CI: confidence interval, HPV: human papilloma virus, RRP: recurrent respiratory papillomatosis, MTI: mean treatment intervals