- Definitions and diagnostic criteria.
| Condition(s) | Definition and diagnostic criteria |
|---|---|
| SGA | BW <P10 (10th percentile) of the average BW of infants having identical GA and gender.13 |
| hsPDA | The diameter of PDA was >1.5 mm, left aortic/atrial diameter was ≥1.3, and bidirectional bi-phase (or left-to-right) shunt was present. In addition, presence of at least one of the following clinical manifestations: tachypnea, cardiac murmur, tachycardia, pulse pressure elevation (>25 mmHg), flushing or cardiac dilation, hypotension, and water pulse or cardiac enlargement.14 |
| NEC | Bell’s staging criteria15 |
| EOS & LOS | The expert consensus on neonatal sepsis diagnosis and management (version 2019)16 |
| Interventional ROP | Surgery (laser or cryocoagulation) or application of bevacizumab |
| FI | Emesis or abdominal distention, gastric residual volume >50% of prior feeding volume, and an enteral feeding reduction, delay, or withdrawal17 |
| MBDP | The expert consensus on clinical management of metabolic bone disease of prematurity18 |
| NRDS, IVH grade III-IV, PVL, and ROP | The 5th edition of practical neonatology19 |
| EUGR | P10 of weight below the growth graph at 36 weeks of modified GA or at discharge in accordance with the Fenton 2013 growth curves20 |
| Days to full enteral feeding | The time obtained for oral milk feeding to attain a 150 mL/kg/day value21 |
| GV following BW regain (g/kg/day) | [1000 × ln (Wn/W1)]/[Dn - D1], where Wn and W1 denote the BWs at discharge and birth, whereas Dn and D1 stand for the overall length of stay and days to regain BW22 |
SGA: small for gestational age, BW: birth weight, GA: gestational age, hsPDA: hemodynamically significant patent ductus arteriosus, PDA: patent ductus arteriosus, NEC: neonatal necrotizing enterocolitis, EOS: early onset sepsis, LOS: late-onset sepsis, ROP: retinopathy of prematurity, FI: feeding intolerance, MBDP: metabolic bone disease of prematurity, NRDS: neonatal respiratory distress syndrome, IVH: intraventricular hemorrhage, PVL: periventricular leukomalacia, ROP: retinopathy of prematurity, EUGR: extrauterine growth retardation, GV: growth velocity