Table 2

- Summary of measurements regarding DNA damage with regard to groups.

ParametersGroup DES (n=15)Group PRO (n=15)P-values (between groups)
Head length (μm)
T122.15±3.8421.36±2.140.494
T222.52±4.5921.75±3.090.598
T324.16±3.2923.17±3.420.429
T423.71±2.8821.54±2.400.033
P-values (repeated measurements)0.2160.211 
Change*1.56±4.910.18±1.870.321
Tail length (μm)
T121.69±1.9519.63±2.830.028
T222.92±3.1918.14±5.500.007
T321.33±3.4218.45±4.230.049
T422.68±3.1119.48±4.740.037
P-values (repeated measurements)0.2190.519 
Change*0.99±3.92-0.16±3.760.421
Head intensity (%)
T180.14±10.0774.82±12.920.218
T275.84±9.0168.96±18.900.214
T378.17±7.0476.17±13.490.615
T478.06±.4877.01±13.050.789
P-values (repeated measurements)0.7400.187 
Change*-2.08±10.632.19±16.900.414
Tail intensity (%)
T123.13±16.4323.34±4.660.964
T223.51±10.0919.98±3.240.208
T322.07±6.8819.19±4.640.190
T421.74±7.4623.17±2.720.492
P-values (repeated measurements)0.8820.353 
Change*-1.39±14.59-0.17±4.920.762
Tail moment
T15.80 (3.74-7.84)3.34 (2.37-8.22)0.152
T23.09 (2.49-5.93)3.38 (2.31-4.65)0.520
T34.85 (1.93-6.43)3.69 (2.40-6.41)0.917
T45.81 (3.62-6.49)3.01 (2.02-4.49)0.036
P-values (repeated measurements)0.1780.564 
Change*-0.18 (-1.06 - 1.42)-0.74 (-3.99 - 0.64)0.254
  • Values are presented as the mean ± standard deviation (SD) for normally distributed continuous variables or median (25th percentile - 75th percentile) for non-normally distributed continuous variables.

  • * Difference between T4 and T1, negative values represent decrease and positive values represent increase.

  • DES: desflurane, PRO: propofol, T1: 5 minutes before anesthesia induction, T2: 2 hours after the initiation of anesthesia, T3: postoperative first day in the morning, T4: postoperative fifth day after anesthesia induction