- Association between sample characteristics and biomarkers in relation to IgG status among hemodialysis patients (N=174).
| Variables | Non-reactive IgG <1.6 mg/dl (n=14) | Reactive IgG ≥ 1.6 mg/dl (n=160) | P-value |
|---|---|---|---|
| Age group, n (%) | |||
| 18- 30 years | 1 (7.14) | 7 (4.38) | 0.070 |
| 31- 40 years | 4 (28.6) | 12 (7.50) | |
| 41- 50 years | 4 (28.6) | 68 (42.5) | |
| >50 years | 5 (35.7) | 73 (45.6) | |
| Gender, n (%) | |||
| Male | 9 (64.3) | 98 (61.3) | 1.000 |
| Female | 5 (35.7) | 62 (38.8) | |
| Cause of renal failure, n (%) | |||
| Hypertension, yes | 10 (71.4) | 134 (83.8) | 0.267 |
| Hypertension, no | 4 (28.6) | 26 (16.3) | |
| Diabetes mellitus, yes | 2 (14.3) | 58 (36.3) | 0.142 |
| Diabetes mellitus, no | 12 (85.7) | 101 (63.1) | |
| Hypertension+ Diabetes mellitus, yes | 0 (0.00) | 41 (25.6) | 0.042* |
| Hypertension+ Diabetes mellitus, no | 14 (100) | 119 (74.4) | |
| Others, yes§ | 2 (14.3) | 9 (5.63) | 0.217 |
| Others, no | 12 (85.7) | 151 (94.4) | |
| Biomarkers | |||
| Albumin, g/dl, mean ± SD | 3.54 ± 0.29 | 3.58 ± 1.21 | 0.543 |
| Median (IQR) | 3.60 (3.20- 3.80) | 3.50 (3.30- 3.73) | |
| Hemoglobin, g/dl, mean ± SD | 10.7 ± 1.55 | 11.0 ± 1.59 | 0.531 |
| Median (IQR) | 10.8 (0.05- 11.8) | 11.0 (10.1- 11.8) | |
| Random glucose, mg/dl, mean ± SD | 134 ± 21.0 | 138 ± 27.4 | 0.604 |
| Median (IQR) | 132 (117- 148) | 130 (119- 166) | |
↵§ Other causes of renal failure include kidney stones, systemic lupus erythematosus, glomerulonephritis, renal hypoplasia. Fisher’s exact test and Mann-Whitney test were used to obtain data presented in table. SD: standard deviation, IQR: interquartile range, IG: immunoglobulin