- Association of Factor I fibrinogen rs6050 C/T polymorphism with recurrent spontaneous miscarriage (RSM) in pregnant Saudi women.
Genotype | RSM pregnant | Control | Patients (RSM pregnant) vs. control | |||||
---|---|---|---|---|---|---|---|---|
n (%) | OR | n (%) | OR | OR | CI | X2 | P-value | |
CC | 7 (14%) | 0.16 | 13 (26%) | 0.35 | 0.46 | 0.17 to 1.28 | 2.23 | 0.14 |
CT | 31 (62%) | 1.63 | 14 (28%) | 0.39 | 4.18 | 1.81 to 9.73 | 11.56 | 0.001 |
TT | 12 (24%) | 0.32 | 23 (46%) | 0.85 | 0.38 | 0.16 to 0.87 | 5.27 | 0.02 |
Total | 50 | 50 | ||||||
Alleles frequencies | ||||||||
C | 45 (45%) | 0.82 | 40 (40%) | 0.67 | 1.22 | 0.70 to 2.15 | ||
T | 55 (55%) | 1.22 | 60 (60%) | 1.5 | 0.81 | 0.46 to 1.43 | 0.51 | 0.48 |
CI: Confidence interval, vs: versus, a p-value of ≤0.05 determined statistical significance, OR: odds ratio, X2: Chi-square