- Comparison of DIGIROP-Screen with other existing retinopathy of prematurity prediction models.
| Type 1 ROP | Total | Sensitivity | Specificity | Disease prevalence | PPV | NPV | Accuracy | AUC |
|---|---|---|---|---|---|---|---|---|
| DIGIROP-Birth | 272 | 94.7 (74.0-99.9) | 43.5 (37.3-49.8) | 7.0 (4.3-10.7) | 11.2 (9.8-12.8) | 99.1 (94.2-99.9) | 47.1 (41.0-53.2) | 0.68 (0.54-0.82) |
| DIGIROP-Screen PNA6w | 272 | 94.7 (74.0-99.9) | 40.7 (34.6-47.0) | 7.0 (4.3-10.7) | 10.7 (9.4-12.2) | 99.0 (93.8-99.9) | 44.5 (38.5-50.6) | 0.65 (0.51-0.79) |
| ROPSCORE alarm | 272 | 100 (82.4-100) | 28.5 (23.0-34.5) | 7.0 (4.3-10.7) | 9.5 (8.9-10.2) | 100 (95.0-100) | 33.5 (27.9-39.4) | 0.63 (0.49-0.77) |
| CO-ROP | 272 | 94.7 (74.0-99.9) | 5.1 (2.8-8.6) | 7.0 (4.3-10.7) | 7.0 (6.3-7.7) | 92.9 (64.2-99.0) | 11.4 (7.9-15.8) | 0.51 (0.34-0.69) |
| HgCO-ROP | 272 | 89.5 (66.9-98.7) | 19.4 (14.7-24.8) | 7.0 (4.3-10.7) | 7.7 (6.6-9.0) | 96.1 (86.6-98.9) | 24.3 (19.3-29.8) | 0.56 (0.39-0.72) |
| WINROP Alarm | 272 | 100 (82.4-100) | 20.2 (15.4-25.6) | 7.0 (4.3-10.7) | 8.6 (8.1-9.1) | 100 (93.0-100) | 25.7 (20.7-31.4) | 0.61 (0.46-0.75) |
| G-ROP 1 | 146 | 100 (76.8-100) | 15.2 (9.5-22.4) | 9.6 (5.3-15.6) | 11.1 (10.4-11.8) | 100 (83.2-100) | 23.3 (16.7-31.0) | 0.58 (0.42-0.73) |
| G-ROP 2 | 146 | 100 (76.8-100) | 9.1 (4.8-15.3) | 9.6 (5.3-15.6) | 10.5 (10.0-11.0) | 100 (73.5-100) | 17.8 (12.0-25.0) | 0.55 (0.38-0.71) |
Values are presented as numbers with 95% confidence intervals. PNA : postnatal age in weeks, ROP: retinopathy of prematurity, CO-ROP: Colorado retinopathy of prematurity, HgCO-ROP: high grade Colorado-retinopathy of prematurity model, WINROP: weight insulin-like growth factor 1 neonatal retinopathy of prematurity, G-ROP: postnatal growth and retinopathy of prematurity, PPV: positive predictive value, NPV: negative predictive value, AUC: area under the curve