Appendix 2

- Literature search of anti-obesity medications in Arab countries - SR the Cochrane Library (CENTRAL).

#SearchesResults
1exp Overweight/25617
2(over-weight or overweight or obese* or obesitas or obesity*).tw,kf,kw.59595
3or/1-2 [Overweight/Obese Concept]62817
4exp Anti-Obesity Agents/2642
5((anti-obesity or antiobesity or anti-obese or antiobese or weight-loss or weightloss or ((body-weight or bodyweight or weight) adj2 (lose? or losing or reduc*))) adj2 (agent? or drug? or medication? or pharmaceutical? or pharmacotherap* or pharma-cotherap* or pharmaco-therap*)).tw,kf,kw. or (aclimostat or ZGN-1061 or ZGN1061).mp. or (beloranib or cdk-732 or cdk732 or zgn-433 or zgn433).mp. or (benfluorex or benfluramate or “SE 780” or “780 SE” or “JP 992” or “S 780”).mp. or (benzphetamine or benzfetamine or benzylamphetamine or benzylmetamphetamine or dextro-benzphetamine or didrex or inapetyl or “l benzphetamine” or “levo benzphetamine” or “n benzyl n methyl 1 phenyl 2 propanamine” or “n benzyl n methylamphetamine” or “n benzyl n,alpha dimethylphenethylamine” or “n benzylmethamphetamine”).mp. or (bio101 or bio-101 or myoda or sarconeos).mp. or (“bupropion hydrochloride, naltrexone hydrochoride drug combination” or (bupropion hydrochloride adj natrexone hydrochloride) or Mysimba or Contrave).mp. or (butenolide or 2-furanone or crotonolactone or 2-B4O or 2-buten-4-olide).mp. or (cagrilintide or am-833 or am833 or nn-9838 or nn9838 or “Nnc-0174 0833” or nnc01740833).mp. or (cetilistat or ATL-962).mp. or (“CGP 71683 A” or CGP71683A or CGP-71683A).mp. or (danuglipron or “pf 06882961” or “pf 06882961 82” or pf06882961 or pf0688296182).mp. or (Diethylpropion or Amfepramon or Amfepramone or Phepranon or 2-Diethylaminopropiophenone or Anorex or Lipomin or Regenon or Dietil-retard or Dietilretard or Regibon or Tenuate or Delgamer or Maruate or Moderatan or Neobes or Nobesine or Propion or Prefamone or Tepanil or “Ifa Norex”).mp. or (efinopegdutide or “hm 12525a” or hm12525a or “jnj 5111” or “jnj 64565111” or jnj5111 or jnj64565111).mp. or (“FG 7142” or “ZK 39106” or “N-methyl-beta-carboline-3-carboxamide”).mp. or gambi-jung.mp. or hm04.mp. or (Islet Amyloid Polypeptide or Pancreatic Amylin or IAPP Protein or Insulinoma Amyloid Polypeptide or Amlintide or Amylin or IAPP Precursor).mp. or (lipid mobili#ing substance? or fat mobili#ing substance? or lipid mobili#ing factor?).mp. or (livoletide or “azp 531” or azp531 or cyclo).mp. or (norpseudoephedrine or pseudonorephedrine or cathine or exponcit or fasupond or Fugoa Depo).mp. or (oleoyl-estrone or Merlin-2).mp. or (Orlistat or Tetrahydrolipstatin or THLP or Tetrahydrolipastatin or Ro-18-0647 or Xenical).mp. or (perflubron or perfluorooctylbromide or perfluorooctyl bromide or PFOB or perfluoroctylbromide or Imagent GI or L-1913 or LA-11063 or LA11063 or perflubron emulsion or AF0144 or perfluorooctyl iodide or perfluorooctyliodide or Imagent BP or Oxygent).mp. or (Phenmetrazine or Oxazimedrine or Fenmetrazin or Defenmetrazin or Phenmetraline or Preludin).mp. or exp Phentermine/ or (Phentermine or Duromine or Adipex-P or AdipexP or Ionamine or Chlorphentermine or Pre-Sate or Desopimon or Avipron or Mephentermine).mp. or phentermine-topiramate.mp. or exp Phenylpropanolamine/ or (Phenylpropanolamine or Norephedrine or Propagest or Prolamine or Triaminic DM or Dexatrim or Metaraminol or meta-Hydroxynorephedrine or Metaradrin or m-Hydroxyphenylpropanolamine or m-Hydroxynorephedrine or Hydroxyphenylpropanolamine or Isophenylephrine or Aramine or Araminol or p-Hydroxynorephedrine or para-Hydroxynorephedrine or Tolterodine Tartrate or Tolterodine or Detrol or Urotrol or PHA-686464B or PHA686464B or Detrusitol or Unidet).mp. or (pyroglutamyl-histidyl-glycine or pGlu-His-Gly-OH or Pyr-His-Gly or colon mitosis inhibitor or pyroGlu-His-GlyOH or pGlu-His-Gly or pyro-Glu-His-Gly-OH or Ro 14-61332 or anorexigenic peptide).mp. or (Rimonabant or SR141716 or SR 141716 or Zimulti or SR-141716A or SR141716A or Acomplia).mp. or Satietin.mp. or (setmelanotide or “bim 22493” or bim22493 or “cam 4072” or cam4072 or imcivree or “irc 022493” or irc022493 or “rm 493” or rm493).mp. or (sibutramine or di-desmethylsibutramine or didesmethylsibutramine or “(R)-DDMS” or Reductil or mono-desmethylsibutramine or sibutramine hydrochloride or “BTS 54 524” or BTS-54524 or Meridia).mp. or (sucunamostat or “sco 792” or sco792 or “tak 792” or tak792).mp. or Topiramate.mp. or (vutiglabridin or “hsg 4112” or hsg4112).mp.5942
6Glucagon-Like Peptide-1 Receptor/ag31
7(((GLP-1 or GLP1 or GLP-1R or GLP1R or glucagon-like peptide-1) adj2 (agonist? or stimulating agent?)) or ((“long acting GLP 1” or “long acting glucagon like peptide 1” or “longacting glucagon like peptide 1”) adj2 agonist?) or albenatide or (albiglutide or albugon or “albumin GLP 1” or “albumin glucagon like peptide 1” or eperzan or “GLP 1 albumin” or “glucagon like peptide 1 albumin” or “gsk 716155” or “gsk 716155a” or gsk-716155 or gsk716155 or Gsk-716155a or gsk716155a or naliglutide or syncria or tanzeum) or beinaglutide or (“cjc 1131” or cjc1131) or (cotadutide or “medi 0382” or medi0382) or (danuglipron or “pf 06882961” or “pf 06882961 82” or pf06882961 or pf0688296182) or (dulaglutide or “ly 05008” or “ly 2189265” or ly05008 or ly2189265 or trulicity) or (ecnoglutide or “xw 004” or xw004) or (efocipegtrutide or “hm 15211” or hm15211) or (efpeglenatide or “hm 11260c” or hm11260c or “LAPS exendin 4” or “sar 439977” or sar439977) or elsiglutide or (exenatide or “ac 002993” or ac002993 or AC-2993 or ac2993 or “ac 2993a” or ac2993a or Bydureon or Byetta or “da 3091” or da3091 or “dlp 414” or dlp414 or “exendin 4” or “Ex4 Peptide” or exenasphere or “ft 228” or ft228 or “itca 650” or itca650 or “ly 2148568” or ly2148568 or “ormd 0901” or ormd0901 or “pt 302” or pt302) or (“insulin degludec plus liraglutide” or ideglira or “insulin degludec/liraglutide” or “liraglutide plus insulin degludec” or “liraglutide/insulin degludec” or “nn 9068” or nn9068 or xultophy or “xultophy 100/3.6”) or (“insulin glargine plus lixisenatide” or “ave 0010 / hoe 901” or “ave0010/hoe901” or “hoe 901 / ave 0010” or “hoe901/ave0010” or iglarlixi or “insulin glargine/lixisenatide” or “lantus/lyxumia” or lixilan or “lixilan l” or “lixilan o” or “lixisenatide plus insulin glargine” or “lixisenatide/insulin glargine” or “lyxumia/lantus” or soliqua or suliqua) or (liraglutide or “4p 004” or 4p004 or “nn 2211” or nn2211 or “nnc 90 1170” or “nnc 90-1170” or “nnc90 1170” or nnc90-1170 or “rd 12014” or rd12014 or Saxenda or Victoza) or (lixisenatide or adlyxin or “aqve 10010” or aqve10010 or “ave 0010” or “ave0010 des 38 proline exendine 4 [1-39]peptidylpentalysyllysinamide” or lyxumia or “zp 10” or zp10) or (“ly 307161” or ly307161) or “lys 40 (nodaga ga 68)nh2 exendin 4” or (mazdutide or “ibi 362” or ibi362 or “ly 3305677” or ly3305677 or “oxm 3” or oxm3) or (pegapamodutide or “ly 2944876” or ly2944876 or “tt 401” or tt401) or (pegloxenatide or “pex 168” or pex168) or (pemvidutide or “alt 801” or alt801 or “sp 1373” or sp1373 or “vpd 107” or vpd107) or (retatrutide or “ly 3437943” or ly3437943) or (semaglutide or Ozempic or Rybelsus or Wegovy or “nn 9535” or nn9535 or “nn 9924” or nn9924 or “nnc 0113 0217” or nnc01130217 or “og 217 sc” or “og 217sc” or og217sc) or (taspoglutide or “bim 51077” or bim51077 or “itm 077” or itm077 or “r 1583” or r1583 or “ro 5073031” or ro5073031) or (tirzepatide or LY3298176 or “ly 3298176” or mounjaro) or utreglutide or (vurolenatide or glp1-xten or “nb 1001” or nb1001 or “nm 002” or nm002 or xten-glp1)).mp. or Carnitine/ or (levocarnitine or “Vitamin BT” or L-Carnitine or Bicarnesine).mp. or Naltrexone-bupropion.mp.8639
8or/4-7 [Anti-Obesity Medication Concept]14719
93 and 8 [Obesity/Overweight + Anti-Obesity Medication]4108
10Algeria/ or Bahrain/ or Comoros/ or Djibouti/ or Egypt/ or Iraq/ or Jordan/ or Kuwait/ or Lebanon/ or Libya/ or Libyan Arab Jamahiriya/ or Mauritania/ or Morocco/ or Oman/ or Palestine/ or Qatar/ or Saudi Arabia/ or Somalia/ or South Sudan/ or Sudan/ or Syrian Arab Republic/ or Tunisia/ or exp United Arab Emirates/ or Yemen/ or Arabs/ or Arab World/ or Africa, Eastern/ or East African People/ or East African/ or Middle East/ or Middle Eastern People/ or “Middle Eastern and North Africans”/ or Africa, Northern/ or North African People/ or North Africa/ or North African/2120
11(Algeria or Algerian? or Bahrain or Manama or Bahraini? or Comoros or Comores or Mayotte or Moroni or Comorian? or Shikomor? or Djibouti or Somaliland or Djiboutian? or Djiboutien? or Egypt or Cairo or “United Arab Republic” or Egyptian? or Iraq or Baghdad or Iraqi? or Jordan or Amman or Transjordan or Jordanian? or Kuwait or Kuweit or Kuwaiti? or Lebanon or Leban* or Liban* or Lubnan* or Lobnan* or Lebanese or Libya or Libia or Libyan? or Tripoli or Mauritania* or Nouakchott or Morrocco or Morocco or Ifni or Rabat or Moroccan? or Oman or Muscat or Omani? or Palestine or Gaza or Ghaza or Ghazza or West Bank or Palestinian? or Qatar or Doha or Katar or Quatar or Qatari? or Saudi? or KSA or Riyadh or Somali? or Mogadishu or South Sudan or Juba or South Sudanese or Sudan or Khartoum or Sudanese or Syria or Damascus or Syrian? or Tunisia or Tunesia or Tunis or Tunisian? or United Arab Emirates or UAE or Abu dhabi or Ajman or Dubai or Sharjah or Trucial state? or Emirati? or Yemen or Aden or Sanaa or “Sana’a” or Yemeni? or East Mediterranean or Eastern Mediterranean or EMRO or Levant or Levantine? or (MENA adj2 region?) or Arab? or Arabia or Arabian? or Arabic World or East African? or Eastern Africa or Eastern African? or Middle East or MENA or Middle Eastern? or Maghreb or North Africa? or Northern Africa? or Meghrebis or Meghrebian?).ab,cp,in,jw,kw,lg,ti.24601
12or/10-11 [Arab Countries Concept]24897
139 and 12 [Final set, Obesity/Overweight + Anti-Obesity Medication + Arab Countries Concept]23
14limit 13 to yr=”2023 -Current”3 [2 after duplicates removed]