Yield of prostate cancer screening at a community based clinic in Saudi Arabia

Abdulaziz A. Almutairi, Abdelmoneim M. Edali, Shoaib A. Khan, Wala A. Aldihan, Abdullah H. Alkhenizan

Abstract


Objectives: To estimate the incidence and prevalence of prostate cancer in Saudi Arabia.

Methods: This is a retrospective cohort study including male patients aged 40 years and over. The prostate-specific antigen screening tests were carried out in a community-based clinic affiliated with King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia between September 2002 and December 2016.

Results: A total of 2,160 male patients were included in the study. Of these, 1,521 (70%) were Saudi nationals and 639 (30%) were non-Saudi nationals. A total of 108 (5%) patients underwent a prostate biopsy. The biopsy results confirmed that 31 (2%) Saudi patients and 6 (0.93%) non-Saudi patients had prostate adenocarcinoma. The age-standardized incidence rate of prostate cancer in the Saudi male population is 70 per 100,000 males. Nearly two-thirds (71%) of the Saudi patients’ prostate cancer was found to be in the early stages. 

Conclusion: The prevalence of prostate cancer in the Saudi male population is higher than that reported by the Saudi Cancer Registry; however, it is low compared with prevalences in developed countries. The mortality rate is also very low. Prostate-specific antigen screening in Saudi Arabia should not be carried out routinely; instead, it should only be carried out on an individual basis. 

 

 

 

Saudi Med J 2019; Vol. 40 (7): 681-686
doi: 10.15537/smj.2019.7.24256

 

How to cite this article:
Almutairi AA, Edali AM, Khan SA, Aldihan WA, Alkhenizan AH. Yield of prostate cancer screening at a community based clinic in Saudi Arabia. Saudi Med J 2019; 40(7): 681-686. doi: 10.15537/smj.2019.7.24256.


Keywords


prostate cancer; screening; Saudi Arabia; cohort

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References


Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. CA Cancer J Clin 2016; 66: 7-30.

Chen R, Ren S, Chinese Prostate Cancer Consortium, Yiu MK, Fai NC, Cheng WS, et al. Prostate cancer in Asia: a collaborative report. Asian J Urol 2014; 1: 15-29.

Al-Zahrani AS, Al-Mutlaq HM, Radwi AN, Bazarbashi SM. Cancer incidence reports Saudi Arabia 2014. Riyadh: Saudi Health Council; 2017. p. 83

Alghamidi IG, Hussain II, Alghamdi MS, El-Sheemy MA. The incidence rate of prostate cancer in Saudi Arabia: an observational descriptive epidemiological analysis of data from the Saudi Cancer Registry 2001-2008. Hematol Oncol Stem Cell Ther 2014; 7: 18-26.

Rabah DM, Arafa MA. Prostate cancer screening in a Saudi population: an explanatory trial study. Prostate Cancer Prostatic Dis 2010; 13: 191-194.

Carter HB, Albertsen PC, Barry MJ, Etzioni R, Freedland SJ, Greene KL, et al. Early detection of prostate cancer: AUA guideline. J Urol 2013; 190: 419-426

Moyer VA, U.S. Preventive Services Task Force. Screening for prostate cancer: US Preventive Services Task Force recommendation statement. Ann Intern Med 2012; 157: 120-134.

Bell N, Gorber SC, Shane A, Joffres M, Singh H, Dickinson J, et al. Recommendations on screening for prostate cancer with the prostate-specific antigen test. CMAJ 2014; 186: 1225-1234.

Mottet N, Bellmunt J, Bolla M, Briers E, Cumberbatch MG, De Santis M, et al. EAU-ESTRO-SIOG guidelines on prostate cancer. Part 1: screening, diagnosis, and local treatment with curative intent. Eur Urol 2017; 71: 618-629.

Segi M, Kurihara M, Tsukahara Y. Cancer Mortality for Selected Sites in 24 Countries: No. 4 (1962-63). Tohoku University, School of Medicine. Department of Public Health; 1966.

Saudi Census. General Authority for Statistics. [Updated 2019. Accessed 2018 February 16th]. Available from: https://www.stats.gov.sa/ar/13

World Cancer Research Fund. American Institute for Cancer Research. Age standardized incidence rate of prostate cancer. [Updated 2007. Accessed 2017 September 9th]. Available from: http://www.wcrf.org/int/cancer-facts-figures/data-specific-cancers/prostate-cancer-statistics

Walter LC, Fung KZ, Kirby KA, Shi Y, Espaldon R, O’Brien S, et al. Five-year downstream outcomes following prostate-specific antigen screening in older men. JAMA Intern Med 2013; 173: 866-873.

Hoffman RM, Gilliland FD, Adams-Cameron M, Hunt WC, Key CR. Prostate-specific antigen testing accuracy in community practice. BMC Fam Pract 2002; 3: 19.

Zahir ST, Nazemian MR, Zand S, Zare S. Survival of patients with prostate cancer in Yazd, Iran. Asian Pac J Cancer Prev 2014; 15: 883-886.

Carter, H. Ballentine, Jonathan I. Epstein, Alan W. Partin. Influence of age and prostate-specific antigen on the chance of curable prostate cancer among men with nonpalpable disease. Urology 1999; 53: 126-130.

Pourmand G, Salem S, Mehrsai A, Lotfi M, Amirzargar MA, Mazdak H, et al. The risk factors of prostate cancer: a multicetric case-control study in Iran. Asian Pac J Cancer Prev 2007; 8: 422-428.

O’Malley RL, Taneja SS. Obesity and prostate cancer. Can J Urol 2006; 13 Suppl 2: 11-17.

Yu XQ, Luo Q, Smith DP, Clements MS, O’Connell DL. Prostate cancer prevalence in New South Wales Australia: A population-based study. Cancer Epidemiol 2015; 39: 29-36.

Romero FR, Romero AW, Almeida RM, Tambara Filho R. The prevalence of prostate cancer in Brazil is higher in Black men than in White men: systematic review and meta-analysis. Int Braz J Urol 2012; 38: 440-447.

Safarinejad MR. Population-based screening for prostate cancer by measuring free and total serum prostate-specific antigen in Iran. Ann Oncol 2006; 17: 1166-1171.

Çeber E, Şimşir A, Umar DÇ, Karababa AO, Günaydın G, Çal Ç, et al. Prevalence of prostate cancer among men aged 40+ living in Osman Gazi health care district. Asian Pac J Cancer Prev 2010; 11: 473-478.


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