Awareness of spina bifida among family of affected child. A cross sectional questionnaire

Sharifah A. Othman, Abdulrazaq AlOjan, Mohammed AlShammari, Ahmed Ammar

Abstract


Objectives: To evaluate the awareness of spina bifida (SB), risk factors and possible preventive measures among mothers who had been following in our clinic with a spina bifida affected child.

 

Methods: A cross-sectional questionnaire-based study with 38 mothers of SB patients who are following at SB and hydrocephalus clinic at King Fahad University Hospital, Khobar, Eastern Province, Saudi Arabia.


Results: Thirty-eight mother were included in this questionnaire. Most of the participants were Saudi (94.7%). Ten out of 38 women (26.3%) had used medications during pregnancy (pain medications and herbal drugs), 4 out of 38 (10.5%) had been exposed to imaging radiation, while 9 (23.7%) had experienced moderate to high grade fever (39-41°C) during pregnancy. Moreover, the majority (86.8%) of these women did not receive folic acid (FA) before pregnancy, and 42.1% of them did not have FA during their first trimester. Only one (2.6%) gave positive family history of SB while, 6 (15.8%) reported having other SB children. 

 

Conclusion: There is a considerably low level of awareness in mothers of SB patients despite prevalence of this anomaly in the Eastern province. This necessitates an effort from health care providers to educate the community about this birth defect entity. Furthermore, genetic counseling should be encouraged especially in those who have a positive familial history for better understanding. Also, larger sample size with randomized controlled trials and larger epidemiological studies should be implemented.

 

 

 

Saudi Med J 2019; Vol. 40 (7): 727-731
doi: 10.15537/smj.2019.7.24264

 

How to cite this article:
Othman SA, AlOjan A, AlShammari M, Ammar A. Awareness of spina bifida among family ofaffected child: A cross sectional questionnaire. Saudi Med J 2019; 40 (7): 727-731. doi: 10.15537/smj.2019.7.24264.

 


Keywords


spina bifida; neural tube defects; awareness; knowledge; FA

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References


AlShail E, De Vol E, Yassen A, Elgamal EA. Epidemiology of neural tube defects in Saudi Arabia. Saudi Med J 2014; 35(Suppl 1): S68-S71.

Centers for Disease Control and Prevention (CDC). Spina bi da and anencephaly before and after folic acid mandate-- United States, 1995-1996 and 1999-2000. MMWR Morb Mortal Wkly Rep 2004; 53: 362-365.

Shibuya K, Murray CJ. Congenital anomalies. In: Murray CJ, Lopez AD, editors. Health dimensions of sex and reproduction: the global burden of sexually transmitted diseases, HIV, maternal conditions, perinatal disorders, and congenital anomalies. Boston (MA): Harvard School of Public Health on behalf of the World Health Organization and the World Bank; 1998. p. 455-512.

Seidahmed M, Abdelbasit O, Shaheed M, Alhussein K, Miqdad A, Khalil M et al. Epidemiology of neural tube defects. Saudi Med 2014; 35 (suppl 1): S29-S35.

Roper WL. Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. MMWR 1992; 41: 001.

Laurence KM, James N, Miller MH, Tennant GB, Campbell H. Double-blind randomised controlled trial of folate treatment before conception to prevent recurrence of neural-tube defects. Br Med J (Clin Res Ed) 1981; 282: 1509-1511.

Al-Holy M, Eideh A, Epuru S, Abu-Jamous D, Ashankyty I. Awareness of FA Intake among Women in the Childbearing Age in Hail Region-Saudi Arabia. Food and Nutrition Sciences. 2013; 4: 49-55.

Kanit H, Ozkan AA, Oner SR, Ispahi C, Endrikat JS, Ertan K. Chromosomal abnormalities in fetuses with ultrasonographically detected neural tube defects. Clin Dysmorphol 2011; 20: 190-193.

Sarmast AH, Laharwal MA, Ramzan AU, Wani AA, Malik NK. A single center study of epidemiology of neural tube defects. J Neurosci Rural Pract 2016; 7: 462-465.

Masihi S, Barati M, Marfu J, Eskandari Z. Detection of neural tube defect in the first and second trimester of pregnancy by ultrasound in Imam Hospital, Ahwaz between December 2008-2010. Iran J Reprod Med 2012; 10: 549-554.

Copp AJ, Greene ND. Genetics and development of neural tube defects. J Pathol 2010; 220: 217-230.

Copp AJ, Adzick NS, Chitty LS, Fletcher JM, Holmbeck GN, Shaw GM. Spina Bifida. Nat Rev Dis Primers 2015; 1: 15007.

Moretti ME, Bar-Oz B, Fried S, Koren G. Maternal hyperthermia and the risk for neural tube defects in offspring: systematic review and meta-analysis. Epidemiology 2005; 16: 216-219.

Buyukkurt S, Binokay F, Seydaoglu G, Gulec UK, Ozgunen FT, Evruke C, et al. Prenatal determination of the upper lesion level of spina bifida with three-dimensional ultrasound. Fetal Diagn Ther 2013; 33: 36-40.

Fehr KR, Fehr KD, Protudjer JLP. Knowledge and use of FA: in women of reproductive age. Can J Diet Pract Res 2011; 72: 197-200.

Al Rakaf MS, Kurdi AM, Ammari AN, Al Hashem AM, Shoukri MM, Garne E, et al. Patterns of FA use in pregnant Saudi women and prevalence of neural tube defects-Results from a nested case-control study. Prev Med Rep 2015; 2: 572-576.

Safdar OY, Al-Dabbagh AA, Abuelieneen WA, Kari JA. Decline in the incidence of neural tube defects after the national fortification of flour (1997-2005). Saudi Med J 2007; 28: 1227-1229.


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