Comparison of quality of life in children undergoing peritoneal dialysis versus hemodialysis

Ola A. Alhusaini, Lamis A. Wayyani, Hadeer E. Dafterdar, Mariyah M. Gamlo, Zainab A. Alkhayat, Abeer S. Alghamdi, Osama Y. Safdar


Objectives: To record pediatric end stage renal disease (ESRD) patients’ quality of life (QOL) in relation to peritoneal dialysis (PD) and hemodialysis (HD). Chronic kidney disease is a rising global epidemic yielding worldwide prevalence of 11-13%. It could possibly lead to ESRD, thus imposing serious burdens on patients and reducing their QOL. These burdens may affect their family members as well.


Methods: This cross-sectional study examined 23 pediatric ESRD patients aged 2-18 years who were undergoing peritoneal dialysis and hemodialysis at King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia, in July 2018. Data were collected using the validated Pediatric Quality of Life InventoryTM 3.0 ESRD Module questionnaire.


Results: The sample included HD (n=9, 40.9%) and PD (n=14, 60.9%) patients. According to the parent-proxy report, we found that the QOL among PD pediatric patients was significantly higher than HD patients (p=0.045). Also, male HD patients had a significantly better QOL on the interaction subscale (70.83±15.95 compared to 30.00±24.00 for females [p=0.023]).


Conclusion:   Quality of life was found to be better among PD pediatric patients in King Abdulaziz University Hospital, Kingdom of Saudi Arabia.


Chronic kidney disease; End-stage renal failure; Hemodialysis; Peritoneal dialysis; Saudi Arabia

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National Kidney Foundation. About chronic kidney disease [Internet]. [Updated 2018; Accessed 2018 June 28]. Available from:

National Kidney Foundation. Dialysis [Internet]. National Kidney Foundation [Updated 2018; Accessed 2018 June 28]. Available from:

Hill NR, Fatoba ST, Oke JL, Hirst JA, O’Callaghan CA, Lasserson DS, et al. Global prevalence of chronic kidney disease - a systematic review and meta-Analysis. PLoS One 2016; 11: e0158765.

World Health Organization. WHOQOL: Measuring quality of life [Internet]. [Updated 2018; Accessed 2018 June 18]. Available from:

Splinter A, Tjaden LA, Haverman L, Adams B, Collard L, Cransberg K, et al. Children on dialysis as well as renal transplanted children report severely impaired health-related quality of life. Qual Life Res 2018; 27: 1445-1454.

Becherucci F, Roperto RM, Materassi M, Romagnani P. Chronic kidney disease in children. Clin Kidney J 2016; 9: 583-591.

Griva K, Kang AW, Yu ZL, Mooppil NK, Foo M, Chan CM, et al. Quality of life and emotional distress between patients on peritoneal dialysis versus community-based hemodialysis. Qual Life Res 2014; 23: 57-66.

Goldstein SL, Graham N, Warady BA, Seikaly M, McDonald R, Burwinkle TM, et al. Measuring health-related quality of life in children with ESRD: performance of the generic and ESRD-specific instrument of the Pediatric Quality of Life Inventory (PedsQL). Am J Kidney Dis 2008; 51: 285-297.

Varni JW. PedsQL translations [Internet]. [Updated 1998; Accessed 2018 July 18]. Available from:

Baek HS, Park KS, Ha IS, Kang HG, Cheong HI, Park YS, et al. Impact of end-stage renal disease in children on their parents. Nephrology (Carlton) 2018; 23: 764-770.

Tjaden LA, Grootenhuis MA, Noordzij M, Groothoff JW. Health-related quality of life in patients with pediatric onset of end-stage renal disease: state of the art and recommendations for clinical practice. Pediatr Nephrol 2016; 31: 1579-1591.

Lopes M, Ferraro A, Koch VH. Health-related quality of life of children and adolescents with CKD stages 4-5 and their caregivers. Pediatr Nephrol 2014; 29: 1239-1247.


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