Hematocrit and the risk of coronary heart disease: The Honolulu Heart Program,☆☆

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  • Association between hematocrit in late adolescence and subsequent myocardial infarction in Swedish men

    2013, International Journal of Cardiology
    Citation Excerpt :

    The association was dose-dependent and largely independent of other factors assessed at baseline. Previous studies conducted in middle-aged populations have also reported an increased risk of coronary artery disease (CAD) at the upper end of the hematocrit distribution [8–15]. Some studies found indications of a dose–response relationship [11–13,15], and others reported very small risk differences at the lower end of the hematocrit distribution [8–10].

  • Usefulness of the blood hematocrit level to predict development of heart failure in a community

    2012, American Journal of Cardiology
    Citation Excerpt :

    In a previous Framingham report, Gagnon et al2 used a 2-year pooled observation method to evaluate the short-term effect of HCT on cardiovascular disease risk and found that low and high HCT levels were associated with increased risk. In contrast, investigators from the Honolulu Heart Study found no association between HCT and CHD.3 Our analysis differs from those studies in several important ways.

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This study was supported by National Heart, Lung and Blood Institute Contract No. NO1-HV-2901.

☆☆

Part of the data contained in this report were presented at the Pacific Basin Cardiovascular Disease Epidemiology Conference, January 19, 1982, at Kona, Hawaii.

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