Case reportKimura disease: diagnostic challenges and clinical management
Section snippets
Case reports
In case 1, in 1979, a 23-year-old Asian man presented with recurrent swelling of his left parotid region after undergoing 2 prior excisions for the same lesion in Taiwan in 1973 and again in 1975. Pathologic diagnoses from these excisions were reportedly consistent with Mickulicz disease. Examination revealed a firm mass over the angle of his jaw without obvious facial nerve involvement and cervical lymphadenopathy (Fig. 1). Laboratory values were remarkable for a peripheral eosinophilia (white
Discussion
Kim and Szeto [1] are reported to be the first to describe this rare inflammatory lesion of the head and neck in 1937, and Kimura et al [2] further classified the disease that is more commonly named after him in 1948. This is a benign disease usually seen in young Asian men with a peak incidence in the third decade [3], [4]. Rarely, these lesions have been reported in non-Asian patients. Kim-Kimura disease or Kimura disease characteristically involves the major salivary glands or lymph nodes in
Conclusion
Here, we present 2 cases of Kimura disease diagnosed in a single surgeon's practice of over 35 years, illustrating the rarity of this lesion. Salient features of the tumor are the atypical presentation of a firm mass in the head and neck, usually in young Asian men. Although most lesions will be associated with the parotid gland or the lymphatics of the neck, unusual locations must be considered. The innumerable minor salivary glands located throughout the oral cavity may give rise to these
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