Gender differences in PTSD symptoms: An exploration of peritraumatic mechanisms

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Abstract

Females are at higher risk than males for developing posttraumatic stress disorder symptoms (PTSS) following exposure to trauma, which may stem from gender differences in initial physiological and psychological responses to trauma. The present study aimed to examine a number of peri- and initial posttraumatic reactions to motor vehicle accidents (MVAs) to determine the extent to which they contributed to gender differences in PTSS. 356 adult MVA survivors (211 males and 145 females) reported on peritraumatic dissociation, perception of life threat and initial PTSS. In addition, heart rate and urinary cortisol levels were collected in-hospital. 6 weeks and 6 months later, PTSS were assessed via clinical interviews. Results suggested that initial PTSS and peritraumatic dissociation were marginally significant mediators at 6-week follow-up and significant mediators at 6-month follow-up, providing partial support for the hypothesis that initial responses to trauma may account for observed gender differences in PTSS development.

Research highlights

▶ Females report more PTSD symptoms than males after motor vehicle accidents. ▶ In hospital, females report higher initial PTSS and dissociation than males. ▶ No gender differences found in cortisol, heart rate or injury severity. ▶ Subjective, not objective responses mediates gender differences in PTSS.

Section snippets

Participants

Three hundred fifty-six non-amnesic MVA victims (211 males and 145 females) were recruited following admission to a hospital trauma unit. The age of participants ranged from 18 to 87 (M = 38.68, SD = 16.16) and average household income was $20,000–30,000 per year. The majority of the sample (89%) was Caucasian, consistent with the demographics of the Northeast Ohio area. At the 6-week follow-up, 251 participants (139 males and 112 females) were retained, and 196 (103 males and 93 females) were

Results

At the 6-week follow-up, 10.36% (6 males and 20 females) met full diagnostic criteria for PTSD and 12.35% (7 males and 24 females) met diagnostic criteria for major depression. At 6 months, 7.14% (2 males and 12 females) met full criteria for PTSD and 12.24% (9 males and 15 females) were clinically depressed. Given the relatively low rates of diagnostic PTSD levels, the following analyses were conducted on continuous PTSS scores.

Discussion

The aim of the present study was to examine peritraumatic and acute-phase factors hypothesized to contribute to gender differences in PTSS following a MVA. Specifically, it was predicted that females would report greater perceived threat, more peritraumatic dissociation, and more initial PTSS than males. It was also hypothesized that PTSS 6-week and 6-month post-MVA would be positively associated with perceived threat, peritraumatic dissociation and initial PTSS, providing further support to

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    Funding for this study was provided by the National Institute of Mental Health (R01 MH62042).

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