Elsevier

Journal of Hepatology

Volume 61, Issue 3, September 2014, Pages 642-659
Journal of Hepatology

Clinical Practice Guidelines
Hepatic Encephalopathy in Chronic Liver Disease: 2014 Practice Guideline by the European Association for the Study of the Liver and the American Association for the Study of Liver Diseases

https://doi.org/10.1016/j.jhep.2014.05.042Get rights and content
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Abbreviations

AASLD
American Association for the Study of Liver Diseases
ACLF
acute-on-chronic liver failure
ALD
alcoholic liver disease
ALF
acute liver failure
BCAAs
branched-chain amino acids
CFF
Critical Flicker Frequency
CHE
covert HE
CLD
chronic liver disease
CRT
Continuous Reaction Time
CT
computed tomography
DM
diabetes mellitus
EASL
European Association for the Study of the Liver
EEG
electroencephalography
GI
gastrointestinal
GRADE
the Grading of Recommendation Assessment, Development, and Evaluation
GCS
Glasgow Coma Scale
GPB
glyceryl phenylbutyrate
HCV
hepatitis C virus
HE
hepatic encephalopathy
HM
hepatic myelopathy
ICT
Inhibitory Control Test
ISHEN
International Society for Hepatic Encephalopathies and Nitrogen Metabolism
IV
intravenous
LOLA
L-ornithine L-aspartate
LT
Liver transplantation
MHE
minimal HE
MR
magnetic resonance
OHE
overt HE
PH
portal hypertension
PHES
Psychometric Hepatic Encephalopathy Score
PP
portal pressure
PSE
portosystemic encephalopathy
PSS
portosystemic shunting
RCT
randomized, controlled trial
TIPS
transjugular intrahepatic portosystemic shunt
VB
variceal bleeding
WHC
West Haven Criteria
WM
working memory

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Contributors: Chairman: Hendrik Vilstrup. Clinical Practice Guideline Members: Piero Amodio, Jasmohan Bajaj, Juan Cordoba (Deceased) , Peter Ferenci, Kevin D. Mullen, Karin Weissenborn, Philip Wong. AASLD/EASL Practice Guideline Subcommittee on Hepatic Encephalopathy: Jayant A. Talwalkar (Chair, AASLD), Hari S. Conjeevaram, Michael Porayko, Raphael B. Merriman, Peter L.M. Jansen, Fabien Zoulim.

This guideline has been approved by the American Association for the Study of Liver Diseases and the European Association for the Study of the Liver and represents the position of both associations.

These guidelines were developed by AASLD and EASL and are published simultaneously in Hepatology (volume 60, issue 2) and the Journal of Hepatology (volume 61, issue 3).