Original ArticleCerebral Venous Thrombosis in a Mexican Multicenter Registry of Acute Cerebrovascular Disease: The RENAMEVASC Study
Section snippets
Patients
This prospective, hospital-based multicenter registry was conducted between November 2002 and October 2004 in 25 referral centers from 14 states of Mexico. All investigators were neurologists trained in cerebrovascular disease. The complete methodology of the RENAMEVASC study has been reported elsewhere.16, 17 Briefly, consecutive patients were registered if a suspected acute cerebrovascular disease was confirmed and accurately classified by computed tomographic (CT) or magnetic resonance
Results
The RENAMEVASC registry included 2000 hospitalized patients with all types of acute cerebrovascular disease. In all, 59 (2.97%; 95% CI, 2.3-3.8%) had CVT. There were 50 (85%) women and 9 (15%) men (female:male ratio, 5:1), with a median age of 31 years (interquartile range, 22-39 years). A total of 45 (76%) patients were younger than 40 years of age. The median time from neurologic symptoms to hospital presentation was 48 hours (interquartile range, 15-96 hrs). Only 1 case of CVT was identified
Discussion
The RENAMEVASC study is the first collaborative, nongovernmental, non–industry sponsored registry on patients hospitalized with all-type acute cerebrovascular disease. In this registry, we observed 3% of cases with CVT among all stroke types. In other countries, the relative frequency ranges from 0.5% to 2%.2, 5, 9, 10 However, in autopsy studies, CVT has been observed in a relative frequency of as much as 10%,19 which suggests that CVT is often clinically overlooked. Here we observed a very
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2021, Journal of Stroke and Cerebrovascular DiseasesCitation Excerpt :Without access to MR, misdiagnosis of severe presentations forms of CVT may also easily occur, in particular in the differential diagnosis with more prevalent conditions such as meningitis, cerebral complications of HIV, cerebral malaria and arterial stroke. In comparison to descriptive epidemiological information from high- and middle-income countries3,33,34,35 (Supplemental Table 4), the sex distribution and clinical manifestations of CVT in Sub-Saharan Africa appear to be similar. Many CVT cases were confirmed by CT alone.