Skip to main content
Log in

Gastric Emptying in Spinal Cord Injury Patients

  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

Abstract

Prolonged gastric emptying half-time (GET1/2)has been observed in several neurological disorders.However, findings of altered gastric emptying (GE) inprevious studies on subjects with spinal cord injuries (SCI) have been questioned. Thus, GET1/2 ofsolid meals in SCI patients was studied by radionuclideimaging. This prospective study was conducted to assessGET1/2 in 50 SCI patients using radionuclide labeled solid meals. GET1/2 was abnormal in 58% of the50 SCI patients. Age (abnormal GET1/2 in 57% of young vs59% of old patients) and injury duration (abnormalGET1/2 in 61% of long vs 56% of short duration patients) were not statistically significantfactors influencing GET1/2 (P > 0.05). However, theincidences of abnormal GET1/2 in female SCI patients(57%) and patients with high level injury (quadriplegic) (83%) were higher than in male SCI patients(47%) and patients with low level injury (paraplegic)(35%) (P < 0.05). SCI can cause significant prolongedGE of a solid meal, especially in female patients and patients with high level injury.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. Rajendran SK, Reiser JR, Bauman W, Zhang RL, Gordon SK, Korsten MA: Gastrointestinal transit after spinal cord injury: effect of cisapride. Am J Gastroenterol 87:1614–1617, 1992

    Google Scholar 

  2. Kewalramani L: Neurogenic gastroduodenal ulceration and bleeding associated with spinal cord injuries. J Trauma 19:259–265, 1979

    Google Scholar 

  3. Schuster M: Motor disorders of the stomach. Med Clin North Am 65:1269–1289, 1981

    Google Scholar 

  4. Zhang RL, Chayes Z, Korsten MA, Bauman WA: Gastric emptying rates to liquid or solid meals appear to be unaffected by spinalcord injury. Am J Gastroenterol 89:1856–1858, 1994

    Google Scholar 

  5. Segal JL, Milne N, Brunnemann SR: Gastric emptying is impaired in patients with spinal cord injury. Am J Gastroenterol 90:466–470, 1995

    Google Scholar 

  6. Segal JL, Milne N, Brunnemann SR, Lyons KP: Metoclopramide-induced normalization of impaired gastric emptying in spinal cord injury. Am J Gastroenterol 82:1143–1148, 1987

    Google Scholar 

  7. Fealey RD, Szurszewski JH, Merritt JL, DiMagno EP: Effect of traumatic spinalcord transection on human upper gastrointestinal motility and gastric emptying. Gastroenterology. 87:69–75, 1984

    Google Scholar 

  8. Kao CH, Lai T L, Wang SJ, Chen GH, Yeh SH: Influence of age on gastric emptying in healthy Chinese. Clin Nucl Med 19:401–404, 1994

    Google Scholar 

  9. Malmud LS, Fisher RS, Knight LC, Rock E: Scintigraphic evaluation of gastric emptying. Semin Nucl Med 8:116–125, 1982

    Google Scholar 

  10. Elashoff JD, Reedy TJ, Meyer JH: Analysis of gastric emptying data. Gastroenterology 83:1306–1312, 1982

    Google Scholar 

  11. Griffith GH, Owen GM, Kirkman S, Shields R: Measurement of rate of gastric emptying using chromium-51. Lancet i:1244–1245, 1966

    Google Scholar 

  12. Christian PE, Datz F L, Moore JG: Technical considerations in radionuclide gastric emptying studies. J Nucl Med Technol 15:200–207, 1987

    Google Scholar 

  13. Datz FL, Christian PE, Moore J: Gender-related differences in gastric emptying. J Nucl Med 28:1204–1207, 1987

    Google Scholar 

  14. Nino-Murcia M, Friedland GW: Functional abnormalities of the gastrointestinal tract in patients with spinalcord injuries: Evaluation with imaging procedures. Am J Radiol 158:279–281, 1992

    Google Scholar 

  15. Schapiro H, Woodward ER: Pathway of enterogastric reflex. Proc Soc Exp Biol Med 101:407–409, 1959

    Google Scholar 

  16. Chaudhuri TK: Use of Tc-99m DTPA for measuring gastric emptying time. J Nucl Med 15:391–395, 1974

    Google Scholar 

Download references

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kao, CH., Ho, YJ., Changlai, SP. et al. Gastric Emptying in Spinal Cord Injury Patients. Dig Dis Sci 44, 1512–1515 (1999). https://doi.org/10.1023/A:1026690305537

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1026690305537

Navigation