CASE REPORT
Successful recovery of COVID-19 pneumonia in a renal transplant recipient with long-term immunosuppression

https://doi.org/10.1111/ajt.15869Get rights and content
Under a Creative Commons license
open archive

The current outbreak of Coronavirus Disease 2019 (COVID-19) has raised great concern worldwide, but its impact on transplant recipients is unknown. We report here the clinical features and therapeutic course of the first reported renal transplant recipient with confirmed COVID-19 pneumonia. This is a 52-year-old man who received kidney transplantation 12 years ago. His overall clinical characteristics (symptoms, laboratory examinations, and chest CT) were similar to those of non-transplanted COVID-19 patients. Following a treatment regimen consisting of reduced immunosuppressant use and low dose methylprednisolone-based therapy, the COVID-19 pneumonia in this long-term immunosuppressive patient was successfully recovered. This effectively treated case has reference value for the future treatment of other transplant patients with COVID-19 pneumonia.

KEYWORDS

coronavirus
COVID-19
immunosuppression
pneumonia
renal transplantation

Abbreviations

COVID-19
coronavirus disease 2019
CRP
C-reactive protein
CT
computed tomography
eGFR
estimated glomerular filtration rate
ESR
erythrocyte sedimentation rate
IL
interleukin
IVIG
intravenous immunoglobulin
MMF
mycophenolate mofetil
MP
methylprednisolone
PCR
polymerase chain reaction
Pred
prednisone
Scr
serum creatinine
Tac
tacrolimus
TNF-ɑ
tumor necrosis factor alpha

Cited by (0)