Circulation Journal
Online ISSN : 1347-4820
Print ISSN : 1346-9843
ISSN-L : 1346-9843
Clinical Investigation
Activity Monitoring in Heart Failure Patients With Cardiac Resynchronization Therapy
Mihoko KawabataCecilia FantoniFrancois RegoliSanti RaffaFrancesca PastoriSimona FratiniJohn PrenticeHelmut U. KleinAngelo Auricchio
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JOURNAL FREE ACCESS

2007 Volume 71 Issue 12 Pages 1885-1892

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Abstract

Background Cardiac resynchronization therapy (CRT) improves functional capacity in heart failure patients. This study aimed to prospectively analyze long-term device-based monitoring of physical activity in patients undergoing CRT. Methods and Results The Activity Log Index (ALI), calculated by CRT devices, represents the percentage of time when acceleration exceeds a threshold and monitors the physical activity. Data from 178 CRT patients (New York Heart Association III 91%, left ventricular ejection fraction 21±6%, left ventricular end-diastolic diameter 69±9 mm, QRS 159±27 ms, sinus rhythm 81%) were retrieved. The ALI increased from a baseline value of 3.6±2.0 to 11.2±4.6 (p<0.005) 104 weeks after initiation of CRT. A plateau was reached at approximately 12 weeks and thereafter ALI remained stable for up to 2 years. The magnitude of the changes in ALI was similar in patients with different etiologies and underlying rhythms. Despite similar values at baseline, elderly patients (≥65 years) exhibited significantly lower ALI values than younger patients during the follow-up and at the plateau (9.5±4.2 vs 13.3±4.8, p<0.001). Conclusions Device-based monitoring of physical activity in CRT patients is feasible. CRT resulted in a large and long-term increase in physical activity. (Circ J 2007; 71: 1885 - 1892)

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© 2007 THE JAPANESE CIRCULATION SOCIETY
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