Chest
Clinical InvestigationsAirwaysEndobronchial Hamartoma
Section snippets
Materials and Methods
The Bronchoscopy Unit of the 12 de Octubre Hospital, a tertiary hospital with 1,800 beds, performed about 31,000 bronchoscopy procedures between 1974 and 1997. Since 1980, this hospital has served as a referral center for endoscopic therapy of endobronchial lesions by rigid bronchoscope and laser therapy.
In this study, we retrospectively analyzed the cases of all patients with bronchial biopsy-proven EH during a period of 23 years. The Bronchoscopy Unit database was analyzed in order to
Results
During the study period, 47 EHs were diagnosed in the Hospital 12 de Octubre. Four patients were excluded because their clinical histories were not available. Forty-three patients were studied (37 men and 6 women), with a mean (± SD) age of 62 ± 12 years (range, 29 to 81 years). Only nine patients were asymptomatic at the time of diagnosis. On presentation, the most frequent clinical symptoms were recurrent respiratory infections or obstructive pneumonia in 16 patients (37%) and hemoptysis in
Discussion
The endobronchial location of the benign hamartoma is a rare occurrence. In a 1950 study of lung carcinoma, bronchial adenoma, and lung hamartoma, Le Roux11 found 3,000 patients with lung carcinomas, 40 with bronchial adenomas, and 27 with lung hamartomas, of which only 8% were EHs. In the largest published series of pulmonary hamartomas, Gjevre et al7 analyzed 215 cases of hamartoma, of which only 1.4% were located endobronchially; the authors concluded that the hamartoma was a benign neoplasm
ACKNOWLEDGMENT
The authors gratefully acknowledge Dr. Robert Stirling for his help in editing this manuscript.
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Presented at the European Respiratory Society Congress in Madrid, October 1999.