Chest
Clinical InvestigationsMyocardial Infarction in the Young: Angiographic Features and Risk Factor Analysis of Patients with Myocardial Infarction at or before the Age of 35 Years
Section snippets
MATERIALS AND METHODS
We reviewed all cardiac catheterization and in-patient hospital records of the first 2,400 consecutive patients undergoing this procedure at Keesler Medical Center between 1978 and 1984. Of those 2,400 patients, 35 patients at or under the age of 35 years (active-duty military personnel) had been catheterized for evaluation after myocardial infarction (during this same period, 28 patients 35 years old or younger were catheterized for evaluation of chest pain not due to myocardial infarction
RESULTS
Of the 35 patients aged 35 years or less (group 1), 31 were men, and four were women. There were seven black and 28 white patients. The mean age was 31.9 years. The mean age of patients over 55 years (group 2) was 61 years, with 87 men and 13 women; 98 were white patients, and two were black. Although the sex distribution was not significantly different between the two groups, the percentage of black patients suffering myocardial infarction was significantly greater in young patients (Table 1).
DISCUSSION
The distribution of lesions in our patients, with a high incidence of normal coronary arteries and single-vessel disease, is in accordance with previous studies,1, 2, 3, 4, 5, 6 as is the paucity of patients with left main coronary artery disease.
Smoking by far was the most common risk factor in young and old patients in our study, and our incidence of 89 percent (31) in the young patients correlates with previously reported data, which ranges from 80 to 86 percent.7, 8, 9 Smoking has been
REFERENCES (17)
- et al.
Myocardial infarction in young adults: risk factors and natural history
Am Heart J
(1983) - et al.
Coronary arteriographic findings in 1,000 women under age 50
Am J Cardiol
(1975) - et al.
Myocardial infarction before age 36 years in women: predominance of apparent nonatherosclerotic events
Am Heart J
(1982) - et al.
Coronary artery disease in young patients: arteriographic and clinical review of 40 cases aged 35 and under
Am Heart J
(1974) - et al.
Stepwise risk stratification soon after acute myocardial infarction
Am J Cardiol
(1983) - et al.
Clinical correlates of coronary cineangiography in young males with myocardial infarction
Am Heart J
(1976) Assessment, risk stratification and prognosis of young patients after myocardial infarction
Cardiovasc Rev and Rpts
(1986)- et al.
Historic and angiographic features of young adults surviving myocardial infarction
Chest
(1979)
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The ideas and opinions expressed in this article are those of the authors and not necessarily those of the United States Air Force.
Manuscript received January 18; revision accepted April 12.