Antimicrobial effect of crude extracts of Nigella sativa on multiple antibiotics-resistant bacteria

Acta Microbiol Pol. 2000;49(1):63-74.

Abstract

Different crude extracts of Nigella sativa were tested for antimicrobial effectiveness against different bacterial isolates. These isolates comprised 16 gramnegative and 6 grampositive representatives. They showed multiple resistance against antibiotics, specially the gramnegative ones. Crude extracts of Nigella saliva showed a promising effect against some of the test organisms. The most effective extracts were the crude alkaloid and water extracts. Gramnegative isolates were affected more than the grampositive ones.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Arthritis, Infectious / microbiology
  • Bacteria / classification
  • Bacteria / drug effects*
  • Bacteria / isolation & purification
  • Bacterial Infections / microbiology
  • Drug Resistance, Microbial
  • Drug Resistance, Multiple
  • Gram-Negative Bacteria / drug effects
  • Gram-Negative Bacteria / isolation & purification
  • Humans
  • Magnoliopsida / chemistry*
  • Microbial Sensitivity Tests
  • Plant Extracts / pharmacology*
  • Plants, Medicinal / chemistry*
  • Synovial Fluid / microbiology*

Substances

  • Anti-Bacterial Agents
  • Plant Extracts