Bacterial pneumonia: comparison between diabetics and non-diabetics

Acta Diabetol. 2001;38(2):77-82. doi: 10.1007/s005920170017.

Abstract

To determine the causative organisms, antimicrobial susceptibility, and outcome of community- and hospital-acquired pneumonia in diabetics and to compare this with non-diabetics, sputum cultures done at King Abdulaziz University Hospital in the period between January 1998 and December 1999 were reviewed. A total of 354 cases were studied, of which 125 (35%) were diabetics. Diabetic patients were older with a male predominance compared to non-diabetics. H. influenza was the commonest pathogen in community-acquired pneumonia (CAP) in both diabetics and non-diabetics, but there was a predominance of Staphylococcus aureus in diabetics compared to non-diabetics. Gram-negative bacilli were the commonest pathogens in hospital-acquired pneumonia (HAP) in both diabetics and non-diabetics. Ampicillin, co-amoxyclav, flouroquinolones, second-generation cephalosporins and erythromycin were used empirically in CAP while aminoglycosides, fluoroquinolones and imipenem were used in HAP in both diabetics and non-diabetics. No significant difference in mortality was found between diabetics and non-diabetics, for either CAP or HAP.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Blood Glucose / analysis
  • Diabetes Complications*
  • Female
  • Haemophilus Infections / drug therapy
  • Haemophilus Infections / epidemiology
  • Haemophilus Infections / microbiology
  • Haemophilus influenzae
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Pneumonia, Bacterial / drug therapy
  • Pneumonia, Bacterial / epidemiology*
  • Pneumonia, Bacterial / microbiology
  • Sex Characteristics
  • Sputum / microbiology
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / epidemiology
  • Staphylococcal Infections / microbiology
  • Streptococcal Infections / drug therapy
  • Streptococcal Infections / epidemiology
  • Streptococcal Infections / microbiology
  • Streptococcus pneumoniae

Substances

  • Anti-Bacterial Agents
  • Blood Glucose
  • Hypoglycemic Agents