High prevalence of apical periodontitis amongst type 2 diabetic patients

Int Endod J. 2005 Aug;38(8):564-9. doi: 10.1111/j.1365-2591.2005.00996.x.

Abstract

Aim: To study the prevalence of AP in patients with and without type 2 diabetes mellitus.

Methodology: In a retrospective cohort study, the records of 38 subjects with diabetes and 32 control subjects were examined. All participants underwent a full-mouth radiographic survey incorporating 14 periapical radiographs. The periapical region of all teeth, excluding third molars, was examined. Periapical status was assessed using the periapical index score. Statistical analyses were conducted using the Cohen's kappa test, analysis of variance and logistic regression.

Results: Apical periodontitis in at least one tooth was found in 81.3% of diabetic patients and in 58% of control subjects (P = 0.040; OR = 3.2; 95% CI = 1.1-9.4). Amongst diabetic patients 7% of the teeth had AP, whereas in the control subjects 4% of teeth were affected (P = 0.007; OR = 1.8; 95% CI = 1.2-2.8).

Conclusions: Type 2 diabetes mellitus is significantly associated with an increased prevalence of AP.

MeSH terms

  • Adult
  • Aged
  • Cohort Studies
  • Diabetes Mellitus, Type 2 / complications*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Periapical Periodontitis / complications*
  • Periapical Periodontitis / diagnostic imaging
  • Periapical Tissue / diagnostic imaging
  • Periodontal Index
  • Radiography
  • Retrospective Studies
  • Root Canal Therapy