[Affection of Bushen Shengjing pill on NO and NOS in testicle and ante-oxidization of rat with spermatogenic cell injury]

Zhongguo Zhong Yao Za Zhi. 2006 Jun;31(11):904-6.
[Article in Chinese]

Abstract

Objective: Discuss the functional mechanism of treating male infertility with Bushen Shengjing pill (BS).

Method: Fill the SD rat with adenine so as to injure the germ cell which will produce the model rat with kidney yang deficiency. Measure the activity of SOD and NOS, the amount of NO and MDA in the testicle.

Result: BS can promote the activity of SOD, reduce the activity of NOS and the amount of NO and MDA.

Conclusion: BS has the function of protecting the germ cell which is closely related to the function that the pill can promote the activity of SOD, reduce the activity of NOS and the amount of NO and MDA.

Publication types

  • English Abstract

MeSH terms

  • Adenine
  • Animals
  • Drug Combinations
  • Drugs, Chinese Herbal / isolation & purification
  • Drugs, Chinese Herbal / pharmacology*
  • Fertility Agents, Male / pharmacology
  • Kidney Diseases / chemically induced
  • Kidney Diseases / metabolism*
  • Male
  • Malondialdehyde / metabolism
  • Nitric Oxide / metabolism*
  • Nitric Oxide Synthase / metabolism*
  • Plants, Medicinal / chemistry
  • Random Allocation
  • Rats
  • Rats, Sprague-Dawley
  • Spermatogenesis / drug effects
  • Superoxide Dismutase / metabolism
  • Testis / metabolism
  • Yang Deficiency / chemically induced
  • Yang Deficiency / metabolism*

Substances

  • Drug Combinations
  • Drugs, Chinese Herbal
  • Fertility Agents, Male
  • Nitric Oxide
  • Malondialdehyde
  • Nitric Oxide Synthase
  • Superoxide Dismutase
  • Adenine