Family history of psychological problems in generalized anxiety disorder

J Clin Psychol. 2008 Jul;64(7):905-18. doi: 10.1002/jclp.20497.

Abstract

The current investigation examined self-reported family history of psychological problems in a large sample of individuals diagnosed with generalized anxiety disorder (GAD) and nonanxious controls. The GAD participants were all individuals receiving cognitive-behavioral therapy as part of two large randomized clinical trials. Family history information was obtained from the Anxiety Disorders Interview Schedule-Revised (ADIS-R; DiNardo & Barlow, 1988). The results indicate that, compared to control participants, individuals with GAD were more likely to have family members with anxiety problems, but not other psychological problems. Possible mechanisms for the familial transmission of GAD are discussed.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / epidemiology*
  • Anxiety Disorders / therapy
  • Chi-Square Distribution
  • Cognitive Behavioral Therapy
  • Control Groups
  • Family*
  • Female
  • Humans
  • Male
  • Mental Disorders / diagnosis
  • Mental Disorders / epidemiology*
  • Mood Disorders / diagnosis
  • Mood Disorders / epidemiology
  • Prevalence
  • Psychiatric Status Rating Scales / statistics & numerical data
  • Risk Factors
  • Sex Factors
  • Substance-Related Disorders / diagnosis
  • Substance-Related Disorders / epidemiology