Depression and anxiety levels in woman under follow-up for breast cancer: relationship to coping with cancer and quality of life

Med Oncol. 2010 Mar;27(1):108-13. doi: 10.1007/s12032-009-9181-4. Epub 2009 Feb 19.

Abstract

Aim: The relation of anxiety and depression levels with characteristics of coping with the disease and quality of life were evaluated in women under follow-up for breast cancer.

Materials and methods: Patients who had presented to the breast cancer polyclinics for follow-up were evaluated. The Beck Depression and the State-Trait Anxiety inventories were used in the evaluation of depression and anxiety levels. In order to evaluate their power to cope with cancer, the patients were questioned for a social support network. EORTC QLQ-C30 and QLQ-BR23 questionnaires were applied for quality of life evaluations.

Results: There were 23 (19%) patients with depression; 3 (2.5%) with grade I anxiety, 94 (77%) grade II, and 23 (19%) grade III anxiety, respectively. Depression and anxiety levels were affected by the following parameters: being unaccompanied by spouse for hospital follow-ups (P < 0.0001); request to get help by a psychologist (P = 0.02); presence of a person to share their problems (P < 0.0001); and using an alternative treatment (P = 0.04). In the quality of life evaluations, difficulty in sleeping, emotional status, fatigue, and body appearance were related with both depression and anxiety (P < 0.05 for all), whereas physical function (P = 0.002), role performance (P = 0.005), cognitive condition (P < 0.0001), social position (P < 0.0001), pain (P < 0.0001), general health (P < 0.0001), treatment methods (P = 0.001), future anxiety (P < 0.0001), and arm symptoms (P = 0.001) were negatively affected in patients with depression.

Conclusion: High depression and anxiety levels in patients under follow-up for breast cancer influence the coping with cancer and quality of life adversely.

MeSH terms

  • Adaptation, Psychological*
  • Adult
  • Aged
  • Aged, 80 and over
  • Anxiety Disorders / epidemiology*
  • Anxiety Disorders / etiology
  • Breast Neoplasms / complications
  • Breast Neoplasms / psychology*
  • Breast Neoplasms / therapy
  • Depressive Disorder / epidemiology*
  • Depressive Disorder / etiology
  • Disease-Free Survival
  • Family
  • Female
  • Follow-Up Studies
  • Humans
  • Middle Aged
  • Quality of Life*
  • Social Support
  • Surveys and Questionnaires