Comparative study of ultrasound and computed tomography for incidentally detecting diffuse thyroid disease

Ultrasound Med Biol. 2014 Aug;40(8):1778-84. doi: 10.1016/j.ultrasmedbio.2014.02.023. Epub 2014 Apr 27.

Abstract

The aim of this study was to compare the diagnostic values of thyroid ultrasound (US) and neck computed tomography (CT) in incidentally detecting diffuse thyroid disease (DTD). A single radiologist made US and CT diagnoses of incidentally detected DTD in 130 consecutive patients before thyroidectomy for various malignancies. Histopathologic examinations confirmed normal thyroid (n = 80), Hashimoto thyroiditis (n = 20), non-Hashimoto lymphocytic thyroiditis (n = 28) and diffuse hyperplasia (n = 2). Receiver operating characteristic curves revealed that the best diagnostic indices of both imaging methods were achieved on the basis of two or more abnormal imaging findings. The sensitivity, specificity and accuracy of US and CT in incidentally detecting DTD by this classification were 72% and 72%, 87.5% and 91.3% and 81.5% and 83.8%, respectively. Thyroid US and neck CT have similar diagnostic values for differentiating incidental DTD from normal thyroid.

Keywords: Autoimmune thyroiditis; Computed tomography; Diffuse thyroid disease; Thyroid; Ultrasound.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Contrast Media
  • Female
  • Humans
  • Incidental Findings*
  • Male
  • Middle Aged
  • ROC Curve
  • Radiographic Image Enhancement / methods
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Thyroid Diseases / diagnostic imaging*
  • Thyroid Diseases / surgery
  • Thyroid Gland / diagnostic imaging*
  • Thyroid Gland / surgery
  • Thyroidectomy / methods
  • Tomography, X-Ray Computed / methods*
  • Ultrasonography
  • Young Adult

Substances

  • Contrast Media