Metastatic gastrointestinal stromal tumor and hypercalcemia in a patient with ulcerative colitis

Saudi Med J. 2006 Oct;27(10):1585-7.

Abstract

A 45-year-old man suffering from intermittent rectal bleeding was diagnosed with ulcerative colitis involving the descending colon and rectum. After 2 years on ulcerative colitis treatment, he presented with metastatic gastrointestinal tumor, liver and peritoneal spread, and a pelvic mass. Interestingly, he was found to have significant hypercalcemia. He was treated with Imatinib with significant symptomatic and clinical response.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Benzamides
  • Colitis, Ulcerative / complications*
  • Colitis, Ulcerative / pathology
  • Gastrointestinal Stromal Tumors / complications*
  • Gastrointestinal Stromal Tumors / drug therapy*
  • Gastrointestinal Stromal Tumors / pathology
  • Humans
  • Hypercalcemia / complications*
  • Hypercalcemia / diagnosis
  • Imatinib Mesylate
  • Liver Neoplasms / secondary*
  • Male
  • Middle Aged
  • Peritoneal Neoplasms / drug therapy
  • Peritoneal Neoplasms / secondary
  • Piperazines / therapeutic use*
  • Protein Kinase Inhibitors / therapeutic use*
  • Pyrimidines / therapeutic use*
  • Rectum / physiopathology
  • Treatment Outcome

Substances

  • Antineoplastic Agents
  • Benzamides
  • Piperazines
  • Protein Kinase Inhibitors
  • Pyrimidines
  • Imatinib Mesylate