Leiomyosarcoma of the bladder in a 16-year-old girl with a history of cyclophosphamide therapy for bilateral retinoblastoma during infancy

Ali A Al-Zahrani; Baher A Kamal; Hamed M Eldarawani; Tariq M Hashim

Leiomyosarcoma of the bladder in a 16-year-old girl with a history of cyclophosphamide therapy for bilateral retinoblastoma during infancy

Saudi Med J. 2006 Apr;27(4):531-3.

Authors

Ali A Al-Zahrani¹, Baher A Kamal, Hamed M Eldarawani, Tariq M Hashim

Affiliation

¹ Department of Urology and Pathology, King Faisal University, King Fahd Hospital of the University, Al-Khobar, Kingdom of Saudi Arabia. ahzhrani@yahoo.com

PMID: 16598333

Abstract

A 16-year-old female with bladder leiomyosarcoma had a history of bilateral retinoblastoma at 6 months of life. She received cyclophosphamide chemotherapy after surgical enucleation. In this report, we discussed the possible role of retinoblastoma or cyclophosphamide as a target for the development of bladder leiomyosarcoma.

Publication types

Case Reports

MeSH terms

Adolescent
Antineoplastic Agents, Alkylating / adverse effects*
Cyclophosphamide / adverse effects*
Eye Enucleation
Female
Humans
Infant
Leiomyosarcoma / chemically induced*
Retinal Neoplasms / drug therapy*
Retinal Neoplasms / surgery
Retinoblastoma / drug therapy*
Retinoblastoma / surgery
Urinary Bladder Neoplasms / chemically induced*

Substances

Antineoplastic Agents, Alkylating
Cyclophosphamide