User profiles for Anwar A. Sayed

Anwar A. Sayed

Department of Medical Microbiology and Immunology
Verified email at alumni.imperial.ac.uk
Cited by 471

The role of CD8+ T-cell clones in immune thrombocytopenia

A Malik, AA Sayed, P Han, MMH Tan… - Blood, The Journal …, 2023 - ashpublications.org
Immune thrombocytopenia (ITP) is traditionally considered an antibody-mediated disease.
However, a number of features suggest alternative mechanisms of platelet destruction. In this …

[PDF][PDF] Challenges and opportunities in the clinical development of immune checkpoint inhibitors for hepatocellular carcinoma

MJ Flynn, AA Sayed, R Sharma, A Siddique… - …, 2019 - Wiley Online Library
After a decade of stagnation in drug development, therapeutic reversal of immune‐exhaustion
with immune checkpoint inhibitors (ICPIs) has been shown to be effective in advanced …

[HTML][HTML] The progressive public measures of Saudi Arabia to tackle Covid-19 and limit its spread

AA Sayed - International Journal of Environmental Research and …, 2021 - mdpi.com
Since the beginning of the global novel coronavirus disease (Covid-19) pandemic, the
response of governments has varied significantly across the world. This was one of the main …

[HTML][HTML] Investigation of TLR2 and TLR4 polymorphisms and Sepsis susceptibility: computational and experimental approaches

…, EEDA Ibrahim, MM Azab, AA Sayed… - International journal of …, 2022 - mdpi.com
Toll-like receptors (TLR) play an eminent role in the regulation of immune responses to
invading pathogens during sepsis. TLR genetic variants might influence individual susceptibility …

[HTML][HTML] The use of neutrophil-to-lymphocyte ratio (NLR) as a marker for COVID-19 infection in Saudi Arabia: a case-control retrospective multicenter study

AA Sayed, AA Allam, AI Sayed, MA Alraey… - Saudi Medical …, 2021 - ncbi.nlm.nih.gov
Objectives: To assess the neutrophil-to-lymphocyte ratio (NLR) diagnostic and prognostic
value in the context of Coronavirus disease-2019 (COVID-19) infection in Saudi Arabia. …

Individual-focused occupational health interventions: A meta-analysis of randomized controlled trials.

S Estevez Cores, AA Sayed, DK Tracy… - … of Occupational Health …, 2021 - psycnet.apa.org
Employee stress and related psychological strain is not only damaging for those that experience
it, but is also costly for employers and society at large. This study aims to evaluate the …

[HTML][HTML] A phase Ib study of pembrolizumab following trans-arterial chemoembolization (TACE) in hepatocellular carcinoma (HCC): PETAL

DJ Pinato, T Cole, B Bengsch, P Tait, AA Sayed… - Annals of …, 2019 - Elsevier
Background The efficacy of TACE is secondary to its dual ischaemic and cytotoxic effect,
which promotes immunogenic tumor cell death. TACE may prime adaptive immunity and …

[HTML][HTML] Assessing the impact of use and trust in different sources of information on COVID-19 vaccination uptake in Saudi Arabia (SA) using the COVID-19 vaccine …

AA Sayed - Tropical Medicine and Infectious Disease, 2022 - mdpi.com
COVID-19 vaccination has been the cornerstone measure to tackle the severe morbidity and
mortality of the ongoing global pandemic. However, vaccine hesitancy and resistance were …

[HTML][HTML] In silico analysis of missense variants of the C1qA gene related to infection and autoimmune diseases

…, HY Abdallah, EEDA Ibrahim, AA Sayed… - Journal of Taibah …, 2022 - Elsevier
Objectives C1q is a key activator of the classical pathway of the complement system and exerts
consequences relating to opsonization and phagocytosis. The C1qA gene is one of three …

[HTML][HTML] The reasons behind COVID-19 vaccination hesitancy among the parents of children aged between 5 to 11 years old in Saudi Arabia

EM Khatrawi, AA Sayed - … Journal of Environmental Research and Public …, 2023 - mdpi.com
Simultaneously with the development of the COVID-19 vaccination plan for minors, it is critical
to understand the reasons related to parental COVID-19 vaccination hesitancy. This study …