Background The neuropeptide substance P is a potential biomarker and therapeutic target
in cancer. The main objectives of this study were to investigate the expression level of …

Intellectual disability is a heterogeneous disease with many genes and mutations influencing
the phenotype. Consanguineous families constitute a rich resource for the identification of …

The aim of this study was to examine the effect of atorvastatin treatment on levels of leptin,
adiponectin and insulin resistance, and their correlation with clinical parameters, in patients …

Intellectual disability etiology still poses a challenge to clinicians and families. Here we
aimed to dissect the genes causing intellectual disability in local families from Jordan. We …

Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease, which leads to
neurodegenerative processes that cause neuron demyelination. MS is multifactorial with uncertain …

Hirschsprung disease (HSCR) is a congenital disorder characterized by the absence of
neuronal ganglions in the intestine, leading to impaired bowel movement and serious …

Age-related macular degeneration (AMD) is a complex genetic disorder with multiple
etiologies. Multiple genes as well as environmental effects are thought to play a role in causing …

Intellectual disability is a common condition with multiple etiologies. The number of
monogenic causes has increased steadily in recent years due to the implementation of next …

Generalized vitiligo is an acquired disorder characterized by progressive, patchy loss of
pigmentation from skin. Vitiligo is the most common disorder of pigmentation; it occurs with a …

Intellectual disability (ID) is a common heterogeneous disease. Many genes have been
implicated in the etiology of ID, yet gene discovery continues at a fast pace. In this study, we …