Novel pyrazolo[3,4-d]pyrimidines: design, synthesis, anticancer activity, dual EGFR/ErbB2 receptor tyrosine kinases inhibitory activity, effects on cell cycle profile and …

…, AE Kassab, AF Zaher, Z Mahmoud - Journal of enzyme …, 2019 - Taylor & Francis
A series of novel pyrazolo[3,4-d]pyrimidines was synthesised. Twelve synthesised compounds
were evaluated for their anticancer activity against 60 human tumour cell lines by NCI (…

Novel pyrazolo [3, 4-d] pyrimidines as potential cytotoxic agents: Design, synthesis, molecular docking and CDK2 inhibition

…, AE Kassab, AF Zaher, Z Mahmoud - Anti-Cancer Agents in …, 2019 - ingentaconnect.com
Background: Pyrazolo[3,4-d]pyrimidine scaffold was reported to possess potent cytotoxic
and CDK2 inhibitory activity as analogue of roscovitine. Objective: To design and synthesize …

[HTML][HTML] Antifungal and antibacterial investigation of quinary Zr Al Fe Co Ni layered double hydroxide and its Al Fe Co Ni quaternary and Fe Co Ni tertiary roots

R Mahmoud, ZE Eldin, A Khalifa, AAA Anwar… - RSC …, 2024 - pubs.rsc.org
Layered double hydroxides (LDH) are promising 2D nanomaterials being investigated for
several engineering and biomedical applications. In this work, quinary Zr Al Fe Co Ni LDH and …

[HTML][HTML] synthesis and anticancer activity of pyrimido [4, 5-b] quinolines in the last twenty years

NSM Ibrahim, HH Kadry, AF Zaher, KO Mohamed - Chemical Papers, 2024 - Springer
Pyrimido [4, 5-b] quinoline is a vital structural motif. The synthesis of pyrimido [4, 5-b] quinolines
has been a challenging topic in medicinal chemistry. A wide range of starting materials …

[PDF][PDF] Stability and control of complex nonlinear systems with application to chemical reactors

AA Zaher - J. Mathematical Control Science & Applications, 2007 - mukpublications.com
This paper introduces a robust strategy for stabilizing complex industrial processes exemplified
by a complex chemical reactor. The design uses a combination of backstepping methods …

[PDF][PDF] MODIFIED KALMAN FILTER TRACKER BASED ON HIDDEN MARKOV MODEL

ENAM Zaher - 2013 - academia.edu
Target Tracking is comprised of two stages; data association and position estimation. Data
association in a noisy multi-target environment is one of the problems that need solving, for …

Immunological efficiency of microbial melanin on bacterial pathogenicity.

N Allam, A El-Zaher, A Allam - International Journal of …, 2020 - jcbr.journals.ekb.eg
In our present study, the immunological efficiency of brown Mel1 extracted from Streptomyces
longisporoflavus NR043926 and black Mel2 extracted from Aspergillus niger MT355517 …

Recent green approaches for the synthesis of pyrazolo[3,4‐d]pyrimidines: A mini review

M Maher, AF Zaher, Z Mahmoud… - Archiv der …, 2022 - Wiley Online Library
Pyrazolo[3,4‐d]pyrimidine as a bioisostere of purine has drawn considerable attention as a
privileged scaffold for the design and discovery of novel drugs. Green synthesis is an …

[HTML][HTML] Impact of depression and fatigue on relapsing remitting multiple sclerosis in Kingdom of Saudi Arabia

…, AF Albuhassah, AS AlZahrani, AAM Zaher - Saudi Medical …, 2020 - ncbi.nlm.nih.gov
Objectives: To determine relationship between fatigue, depression with the registration in
multiple sclerosis (MS) society activity, and stress with the risk developing a new attack in …

[PDF][PDF] Assessment Accuracy of Static Relative Positioning Using Single Frequency GPS Receivers

MI El-Mewafi, AA Beshr, I Zaher - International Journal of Scientific …, 2015 - researchgate.net
Global Positioning System (GPS) technology today plays a very major role, for surveyors and
geodesists especially for engineering works, mapping, and several geodetic applications. …