User profiles for Bikash Medhi
PROF. BIKASH MEDHIDepartment of Pharmacology, PGIMER Verified email at pgimer.edu.in Cited by 8430 |
In-silico homology assisted identification of inhibitor of RNA binding against 2019-nCoV N-protein (N terminal domain)
The N terminal domain (NTD) of Nucleocapsid protein (N protein) of coronavirus (CoV)
binds to the viral (+) sense RNA and results in CoV ribonucleoprotien (CoV RNP) complex, …
binds to the viral (+) sense RNA and results in CoV ribonucleoprotien (CoV RNP) complex, …
Serum ferritin as a predictive biomarker in COVID-19. A systematic review, meta-analysis and meta-regression analysis
Ferritin is a known inflammatory biomarker in COVID-19. However, many factors and co-morbidities
can confound the level of serum ferritin. This current metaanalysis evaluates serum …
can confound the level of serum ferritin. This current metaanalysis evaluates serum …
Pharmacokinetic and toxicological profile of artemisinin compounds: an update
Artemisinin has been used effectively in malaria treatment. With the emerging resistance to
malaria, the optimum and judicial use of the drug has become important. The drug …
malaria, the optimum and judicial use of the drug has become important. The drug …
Galantamine-loaded solid–lipid nanoparticles for enhanced brain delivery: preparation, characterization, in vitro and in vivo evaluations
Galantamine hydrobromide, a promising acetylcholinesterase inhibitor is reported to be
associated with cholinergic side effects. Its poor brain penetration results in lower bioavailability …
associated with cholinergic side effects. Its poor brain penetration results in lower bioavailability …
Role of vinpocetine in cerebrovascular diseases
A cerebrovascular accident, or stroke, is defined as the abrupt onset of a neurological deficit,
which can be due to ischemia. Cerebral ischemia is caused by a reduction in blood flow …
which can be due to ischemia. Cerebral ischemia is caused by a reduction in blood flow …
Virological and clinical cure in COVID‐19 patients treated with hydroxychloroquine: a systematic review and meta‐analysis
Following the demonstration of the efficacy of hydroxychloroquine against severe acute
respiratory syndrome coronavirus 2 in vitro, many trials started to evaluate its efficacy in clinical …
respiratory syndrome coronavirus 2 in vitro, many trials started to evaluate its efficacy in clinical …
Neuroinflammation in Alzheimer's disease: current progress in molecular signaling and therapeutics
Alzheimer’s disease, a neurodegenerative disease with amyloid beta accumulation as a
major hallmark, has become a dire global health concern as there is a lack of clear …
major hallmark, has become a dire global health concern as there is a lack of clear …
Drug targets for corona virus: A systematic review
…, H Kumar, S Bansal, B Medhi - Indian journal of …, 2020 - journals.lww.com
The 2019-novel coronavirus (nCoV) is a major source of disaster in the 21 th century. However,
the lack of specific drugs to prevent/treat an attack is a major need at this current point of …
the lack of specific drugs to prevent/treat an attack is a major need at this current point of …
A comprehensive review of animal models for coronaviruses: SARS-CoV-2, SARS-CoV, and MERS-CoV
The recent outbreak of coronavirus disease (COVID-19) caused by the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has already affected a large population of …
respiratory syndrome coronavirus 2 (SARS-CoV-2) has already affected a large population of …
Therapeutic options for the treatment of 2019-novel coronavirus: An evidence-based approach
2 Indian Journal of Pharmacology-Volume 52, Issue 1, January-February 2020 also support
these findings and the combined use of IFN‑α and corticosteroid (corticosteroid arm n= 13; …
these findings and the combined use of IFN‑α and corticosteroid (corticosteroid arm n= 13; …