Objectives: This study was performed to evaluate the efficacy of radioactive iodine 131I therapy
of Graves’ hyperthyroidism at Sultan Qaboos University Hospital, Oman and to determine …

Triciribine (TCN) and its 5′-monophosphate (TCN-P) are novel tricyclic compounds with
known antitumor activity; TCN-P is currently in phase II human clinical trials. We now report that …

… (A–C) High-resolution time-lapse recordings of Cx43-GFP GJ plaques acquired at relatively
fast acquisition rates (5 s in A and 6 s in B) reveal the internalization of small vesicles (…

In the absence of an approved and effective vaccine, topical microbicides have become the
strategy of choice to provide women with the ability to prevent the sexual transmission of HIV…

The increasingly prevalent emergence of drug-resistant virus strains in patients being treated
with highly active antiretroviral regimens and the increasing rates of transmission of drug-…

Background The limited success of recent HIV topical pre-exposure prophylaxis clinical trials
highlights the need for more predictive models of drug efficacy that better simulate what …

… described (Buckheit et al., 1994b). The MacSynergy II program was obtained from Dr
Mark Prichard and Dr Charles Shipman at the University of Michigan (Ann Arbor, Mich., USA). …

Background: It has been over 30 years since the first cases of HIV/AIDS and prevention of
infection through vaccination remains elusive. Thus, alternative products, technologies and …

Background: We previously showed the ability of poly (ethylene oxide)-modified
polycaprolactone nanoparticles (PEO-PCL NPs) loaded with dapivirine to modulate genital …

A 48-year-old woman was infected with a vpr-defective human immunodeficiency virus (HIV)-1
molecular clone. Seroconversion was markedly delayed, and without treatment she had …