We describe a 10-year-old boy with a rare large multicystic pulmonary chondroid hamartoma
in the right lower lobe presenting with severe respiratory distress. The radiological …

Breast cancer (BCa) ranks first in incidence rate among cancers in Arab females. The
association between genetic polymorphisms in tumor suppressor genes and the risk of BCa has …

Central nervous system (CNS) metastasis is the most common brain tumor type in adults.
Compared to their primary tumors, these metastases undergo a variety of genetic changes to …

Brain metastases constitute the majority of intracranial cancers, and are often associated
with a poor prognosis. Brain metastasis is a major healthcare burden, especially involving …

The prognosis of glioblastoma has changed little over the past two decades, with only minor
improvements in length of overall survival through the addition of temozolomide (temodal) to …

Pediatric Low Grade Gliomas (PLGGs) display heterogeneity regarding morphology, genomic
drivers and clinical outcomes. The treatment modality dictates the outcome and optimizing …

Mutations in KIF7, the gene that encodes a component of the kinesin complex of anterograde
intraflagellar transport in the cilia, have been reported to cause a range of phenotypes …

Purpose: Next-generation sequencing (NGS) technology detects specific mutations that can
provide treatment opportunities for colorectal cancer (CRC) patients. Patients and Methods: …

Background and aims Hepatocellular carcinoma (HCC) is the third most prevalent cancer in
Saudi Arabia. HCC poses a significant clinical challenge due to the presence of resistance …

INTRODUCTION The incidence of IDH mutations in pediatric glioma is unclear. Recent
publications suggest rates ranging between 0–20%. Therapy poses challenges as it is unclear if …