Treatment of poorly differentiated glioma using a combination of monoclonal antibodies to extracellular connexin-43 fragment, temozolomide, and radiotherapy

…, AV Golanov, SA Goryainov, GE Gorlachev… - Bulletin of experimental …, 2014 - Springer
Antitumor efficiencies of monoclonal antibodies to connexin-43 second extracellular loop (MAbE2Cx43),
temozolomide, and fractionated γ-irradiation in the monotherapy mode and in …

Adversary of DNA integrity: A long non‐coding RNA stimulates driver oncogenic chromosomal rearrangement in human thyroid cells

…, EY Shyrokova, GE Gorlachev… - … Journal of Cancer, 2023 - Wiley Online Library
The flurry of publications devoted to the functions of long non‐coding RNAs (lncRNAs)
published in the last decade leaves no doubt about the exceptional importance of lncRNAs in …

Effects of initial electron beam parameters of a linear accelerator on the properties of bremsstrahlung radiation in a radiotherapy setting

GE Gorlachev, SM Polozov, AV Dalechina… - Physics of Particles and …, 2016 - Springer
The dependence of the initial electron-beam parameters on absorbed dose distributions
have been investigated using a CyberKnife radiotherapy accelerator (Accuray, United States). …

Development of a radiotherapy system based on 6 MeV LINAC and Cone-Beam computer tomograph

…, SA Polikhov, VP Smirnov, GB Sharkov, GE Gorlachev… - Atomic Energy, 2019 - Springer
A system currently under development for remote radiotherapy based on a 6 MeV linac and
cone-beam computer tomograph is presented. Its distinguishing design features and …

Effect of γ-Irradiation on Expression of Tight and Adherens Junction Protein mRNA on In Vitro Blood–Brain Barrier Model

YA Zorkina, NE Volgina, GE Gorlachev… - Bulletin of Experimental …, 2014 - Springer
We studied the effect of γ-irradiation on HUVEC endothelial cells co-cultured with allogeneic
astrocytes. This 2D in vitro model of the blood–brain barrier has the same parameters as …

[PDF][PDF] Diffusion magnetic resonance imaging data: development of methods and tools for diagnosis and treatment of brain diseases

KA Urazova, GE Gorlachev… - Бюллетень …, 2021 - pdfs.semanticscholar.org
The use of quantitative mapping of diffusion characteristics carries great potential for diagnosis
and therapy of brain diseases, since it potentially allows to classify tumors, determine the …

[PDF][PDF] The outcomes of stereotactic radiotherapy in patients with cerebral arteriovenous malformations

…, AN Konovalov, GE Gorlachev… - Zh Vopr Neirokhir Im …, 2015 - scholar.archive.org
Introduction. Cerebral arteriovenous malformations (AVMs) are congenital anomalies of the
cerebral vessel development during the embryonic period. Currently, the conventional …

[PDF][PDF] Histogram based bremsstrahlung radiation source model for the Cyberknife medical linear accelerator

GE Gorlachev, AV Dalechina… - Proc. RUPAC, 2014 - accelconf.web.cern.ch
The accuracy of dose calculations is of fundamental importance in treatment planning of
radiation therapy. The dose distributions must be calculated and verified by an accurate …

Stereotactic radiosurgery in treatment of patients with hypothalamic hamartomas

…, T IuIu, VV Kostiuchenko, GE Gorlachev… - … imeni NN Burdenko, 2010 - europepmc.org
Hypothalamic hamartoma (HH) is malformation of the brain manifesting by paroxysmal
disorders (gelastic seizures) and endocrine disorders (mostly precocious sexual development). …

[PDF][PDF] Blood—Brain Barrier Permeability in Healthy Rats and Rats with Experimental C6 Glioma after Fractionated Radiotherapy of the Brain

…, GV Pavlova, PA Mel'nikov, GE Gorlachev… - … named after NN …, 2015 - researchgate.net
Brain tumors are accompanied by blood-brain barrier (BBB) dysfunction. However, targeted
drug delivery still remains difficult to achieve. Objective. To evaluate the effect of fractionated …